Non-invasive assessment of diameter-dependent cutaneous vascular alterations with age using optical coherence tomography angiography

Takuma Hoshino; Yusuke Hara; Masato Ninomiya; Toyonobu Yamashita; Chika Katagiri; Motoki Oguri; Masako Katsuyama; Yuandong J. Li; Yuxuan Cheng; Nhan M. Le; Ruikang Wang

doi:10.1117/12.2612839

7 March 2022 Non-invasive assessment of diameter-dependent cutaneous vascular alterations with age using optical coherence tomography angiography

Takuma Hoshino, Yusuke Hara, Masato Ninomiya, Toyonobu Yamashita, Chika Katagiri, Motoki Oguri, Masako Katsuyama, Yuandong J. Li, Yuxuan Cheng, Nhan M. Le, Ruikang Wang

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Proceedings Volume PC11934, Photonics in Dermatology and Plastic Surgery 2022; PC119340K (2022) https://doi.org/10.1117/12.2612839
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Aging alterations in dermal blood vessels have been investigated using Optical Coherence Tomography Angiography (OCTA). However, classifying the vessel’s type was previously limited. In this study, we focused on diameter-dependent vascular alterations in facial skin with age, developing 3D analytical methods to the OCTA data with removing tail-artifact. As a result, it was found that the number of micro-vessels, defined at 20–39 microns, decreased with age, which was inversely true for thick vessels (160–179 micron diameter). Our results suggest that the aging degree of dermal vessels may be uniquely assessed by the diameter-dependent vascular alterations using the OCTA.

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Takuma Hoshino, Yusuke Hara, Masato Ninomiya, Toyonobu Yamashita, Chika Katagiri, Motoki Oguri, Masako Katsuyama, Yuandong J. Li, Yuxuan Cheng, Nhan M. Le, and Ruikang Wang "Non-invasive assessment of diameter-dependent cutaneous vascular alterations with age using optical coherence tomography angiography", Proc. SPIE PC11934, Photonics in Dermatology and Plastic Surgery 2022, PC119340K (7 March 2022); https://doi.org/10.1117/12.2612839

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KEYWORDS

Blood vessels

Angiography

Optical coherence tomography

Blood circulation

Skin

Testing and analysis

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