Characterizing 3D and 2D fiber orientation architecture within OCT image sets of the human left atrium

Tirthraj Patel; Yiyi Chen; Christine P. Hendon

doi:10.1117/12.2610096

7 March 2022 Characterizing 3D and 2D fiber orientation architecture within OCT image sets of the human left atrium

Tirthraj Patel, Yiyi Chen, Christine P. Hendon

Proceedings Volume PC11936, Diagnostic and Therapeutic Applications of Light in Cardiology 2022; PC119360I (2022) https://doi.org/10.1117/12.2610096
Event: SPIE BiOS, 2022, San Francisco, California, United States

Conference Poster

Abstract

Optical coherence tomography has been employed to expose and map micron-level cardiac tissue structures. Previous studies have characterized structural substrates like collagen fibers, adipose tissue, scar tissue, and the pulmonary vein region. Cardiac fiber orientation plays a critical role in the electromechanics of the human atria but it has yet to be quantitatively evaluated. Therefore, personalized fiber orientation atlases produced by algorithmic mapping of atrial fiber geometry can serve as models for studying the mechanisms behind AF and cardiac arrhythmias overall. Integration of this algorithm may eventually provide important insights for the guidance of RFA procedures as well.

Conference Presentation

Citation Download Citation

Tirthraj Patel, Yiyi Chen, and Christine P. Hendon "Characterizing 3D and 2D fiber orientation architecture within OCT image sets of the human left atrium", Proc. SPIE PC11936, Diagnostic and Therapeutic Applications of Light in Cardiology 2022, PC119360I (7 March 2022); https://doi.org/10.1117/12.2610096

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