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In this work, we investigate the remodeling of uterine tissue that occurs during the presence of cancer. We acquired de-identified normal and tumor tissue from the Columbia University Medical Center Tissue Bank and used an optical coherence tomography (OCT) system with a 6.5-micron axial resolution to optically characterize the samples. Initial results indicate that the collagen fiber orientation in the cancerous tissue is more heterogeneous than that of the normal tissue.
Arielle Joasil,Haiqiu Yang,Hanina Hibshoosh, andChristine P. Hendon
"Optical coherence tomography enabled tissue architecture characterization of uterine tumors", Proc. SPIE PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI, PC1236809 (6 March 2023); https://doi.org/10.1117/12.2650591
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