A miniaturized frequency-domain near-infrared spectroscopy instrument compatible with the dual-slope method featuring custom ASIC AFE

Alper Kılıç; Giles Blaney; Cristianne Fernandez; Angelo Sassaroli; Sergio Fantini; Valencia M. J. Koomson

doi:10.1117/12.2668684

7 March 2023 A miniaturized frequency-domain near-infrared spectroscopy instrument compatible with the dual-slope method featuring custom ASIC AFE

Alper Kılıç, Giles Blaney, Cristianne Fernandez, Angelo Sassaroli, Sergio Fantini, Valencia M. J. Koomson

Author Affiliations +

Proceedings Volume PC12376, Optical Tomography and Spectroscopy of Tissue XV; PC1237604 (2023) https://doi.org/10.1117/12.2668684
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

In this work, a miniaturized heterodyning FD-NIRS instrument was presented. The device uses a dual slope probe, which removes the need for pre-calibration. The low-footprint system consists of only the circuit board, the probe and a Raspberry-Pi. Four lasers (685 nm and 830 nm) and two avalanche photodiodes are used, where the lasers are modulated with 80 MHz and the APD signals are amplified and downconverted by the analog front end of the instrument: a custom designed fully differential ASIC in 130 nm CMOS technology. Solid phantom measurements revealed <9% error and significant stability for long-term measurements.

Conference Presentation

Citation Download Citation

Alper Kılıç, Giles Blaney, Cristianne Fernandez, Angelo Sassaroli, Sergio Fantini, and Valencia M. J. Koomson "A miniaturized frequency-domain near-infrared spectroscopy instrument compatible with the dual-slope method featuring custom ASIC AFE", Proc. SPIE PC12376, Optical Tomography and Spectroscopy of Tissue XV, PC1237604 (7 March 2023); https://doi.org/10.1117/12.2668684

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