A method for efficient 4D reconstruction of cardio-and hemodynamics in the embryonic mouse using OCT

Andre C. Faubert; Irina V. Larina; Shang Wang

doi:10.1117/12.2649349

7 March 2023 A method for efficient 4D reconstruction of cardio-and hemodynamics in the embryonic mouse using OCT

Andre C. Faubert, Irina V. Larina, Shang Wang

Proceedings Volume PC12378, Dynamics and Fluctuations in Biomedical Photonics XX; PC123780A (2023) https://doi.org/10.1117/12.2649349
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Live imaging of the mouse embryonic heart in 4D (3D+time) is critical for quantitative understanding of the early mammalian cardiac function and development. Optical coherence tomography (OCT) allows for 4D imaging of the cardiodynamics and hemodynamics in the mouse embryo with a unique and important spatiotemporal imaging scale. However, a limited accessibility of the reconstruction method to produce high-quality 4D OCT visualizations of the beating heart acts as a hurdle for a broader application of OCT in studying the embryonic heart. Here, we present an open-source, highly efficient, post-acquisition synchronization method to address this limitation.

Conference Presentation

Citation Download Citation

Andre C. Faubert, Irina V. Larina, and Shang Wang "A method for efficient 4D reconstruction of cardio-and hemodynamics in the embryonic mouse using OCT", Proc. SPIE PC12378, Dynamics and Fluctuations in Biomedical Photonics XX, PC123780A (7 March 2023); https://doi.org/10.1117/12.2649349

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Heart

Optical coherence tomography

Hemodynamics

3D acquisition

3D image processing

Automatic alignment

Confocal microscopy

Show All Keywords

Keywords/Phrases

Search In:

Publication Years