Endoscopic in-vivo hyperspectral imaging for the intraoperative evaluation of head and neck cancer

David Pertzborn; Ayman Bali; Jonas Ballmaier; Mussab Kouka; Anna Mühlig; Ferdinand von Eggeling; Orlando Guntinas-Lichius

doi:10.1117/12.3012020

13 March 2024 Endoscopic in-vivo hyperspectral imaging for the intraoperative evaluation of head and neck cancer

David Pertzborn, Ayman Bali, Jonas Ballmaier, Mussab Kouka, Anna Mühlig, Ferdinand von Eggeling, Orlando Guntinas-Lichius

Author Affiliations +

Proceedings Volume PC12818, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2024; (2024) https://doi.org/10.1117/12.3012020
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

The intraoperative assessment of tumor margins of head and neck cancer is crucial for complete tumor resection and patient outcome. The current standard is to take intraoperatively tumor biopsies for frozen section analysis or to wait for the postoperative final histopathology report. The intraoperative evaluation is time-consuming, subjective, and methodologically limited. Optical methods like hyperspectral imaging (HSI) are of high interest to overcome these limitations. We present a framework to connect in-vivo HSI measurements to ex-vivo histopathological assessments with results as first steps towards the use of HSI as a tool for in-vivo tumor evaluation during head and neck surgery.

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David Pertzborn, Ayman Bali, Jonas Ballmaier, Mussab Kouka, Anna Mühlig, Ferdinand von Eggeling, and Orlando Guntinas-Lichius "Endoscopic in-vivo hyperspectral imaging for the intraoperative evaluation of head and neck cancer", Proc. SPIE PC12818, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2024, (13 March 2024); https://doi.org/10.1117/12.3012020

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