Enhancing multi-layer cerebral analysis in NIRS: a deep learning approach

Jingyi Wu; Jiachen Dou; Jana M. Kainerstorfer

doi:10.1117/12.3001930

13 March 2024 Enhancing multi-layer cerebral analysis in NIRS: a deep learning approach

Jingyi Wu, Jiachen Dou, Jana M. Kainerstorfer

Proceedings Volume PC12828, Neural Imaging and Sensing 2024; PC1282809 (2024) https://doi.org/10.1117/12.3001930
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

In this study, we present a physics-informed deep learning model for predicting partial pathlength and absorption changes in human brain using Near-Infrared Spectroscopy (NIRS). Leveraging the multi-layer modified Beer Lamber Law, our model overcomes the limitations of conventional approach that assumes tissue homogeneity. Trained on synthetic data generated from a multi-layer forward model, out model was tested on Monte Carlo simulations of both two and three-layer geometries, demonstrating robust performance despite encountering varying optical properties and anatomical complexities. Future work will focus on refining the model and testing it on multi-layer optical phantoms and human subjects.

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Jingyi Wu, Jiachen Dou, and Jana M. Kainerstorfer "Enhancing multi-layer cerebral analysis in NIRS: a deep learning approach", Proc. SPIE PC12828, Neural Imaging and Sensing 2024, PC1282809 (13 March 2024); https://doi.org/10.1117/12.3001930

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KEYWORDS

Data modeling

Near infrared spectroscopy

Absorption

Brain tissue

Anatomy

Deep learning

Education and training

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