Presentation
13 March 2024 Investigating in-vivo imaging characteristics of laser-induced CNV mouse with polarization-diversity optical coherence tomography
Author Affiliations +
Abstract
Age-related macular degeneration (AMD) is a leading cause of global irreversible vision loss, with wet AMD responsible for over 90% of AMD-related vision loss. The laser-induced CNV mouse model is commonly used to study wet AMD. For this study, a functional retinal imaging system was used to investigate the pathological characteristics of laser-induced CNV in mice, providing advanced resolution to visualize structural, vascular, and molecular-specific features of the lesions and outer retinal layers.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Jun Song, Jeanne Xi, Joanne A. Matsubara, and Myeong Jin Ju "Investigating in-vivo imaging characteristics of laser-induced CNV mouse with polarization-diversity optical coherence tomography", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128300B (13 March 2024); https://doi.org/10.1117/12.3005706
Advertisement
Advertisement
KEYWORDS
Optical coherence tomography

In vivo imaging

Visualization

Animal model studies

Imaging systems

Mouse models

Spectral calibration

Back to Top