Stimulated Raman scattering in hollow core photonic crystal fiber with potential for human breath analysis for lung cancer detection

Michael Short; Maryam Shirmohammad; Haishan Zeng

doi:10.1117/12.3008762

13 March 2024 Stimulated Raman scattering in hollow core photonic crystal fiber with potential for human breath analysis for lung cancer detection

Michael Short, Maryam Shirmohammad, Haishan Zeng

Author Affiliations +

Proceedings Volume PC12839, Biomedical Vibrational Spectroscopy 2024: Advances in Research and Industry; PC128390K (2024) https://doi.org/10.1117/12.3008762
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

A method for trace gas analysis is presented based on stimulated Raman scattering of the analyte in a hollow core photonic crystal fiber. A single beam pulsed laser excitation was used which realized both fiber enhanced Raman scattering and stimulated Raman scattering, that have significant advantages for improving the detection limit. A system was successfully developed based on the method and tested on hydrogen, carbon dioxide, and propene (C₃H₆) gases. From the results we suggest the method has great potential for analyzing trace complex gases such as volatile organic compounds, which can serve as biomarkers in human breath for lung cancer detection.

Conference Presentation

Citation Download Citation

Michael Short, Maryam Shirmohammad, and Haishan Zeng "Stimulated Raman scattering in hollow core photonic crystal fiber with potential for human breath analysis for lung cancer detection", Proc. SPIE PC12839, Biomedical Vibrational Spectroscopy 2024: Advances in Research and Industry, PC128390K (13 March 2024); https://doi.org/10.1117/12.3008762

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