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13 March 2024 Wavelength and resolution dependency of dynamic optical coherence tomography
Shumpei Fujimura, Ibrahim Abd El-Sadek, Pradipta Mukherjee, Yiheng Lim, Lida Zhu, Rion Morishita, Yuanke Feng, Yoshiaki Yasuno
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Proceedings Volume PC12854, Label-free Biomedical Imaging and Sensing (LBIS) 2024; PC128540D (2024) https://doi.org/10.1117/12.3001490
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
We investigate wavelength and resolution dependency on dynamic optical coherence tomography (D-OCT) signal using two OCT systems. One is 840-nm spectral domain OCT. The other is 1310-nm swept-source OCT. We kept the resolution roughly the same between the two systems by computationally reducing the axial resolution of 840-nm system. In addition, we performed numerical simulation by modeling the intracellular scatterer dynamics by a diffusion. Experimental results showed that longer wavelengths correspond to lower D-OCT, while lower resolutions lead to slightly lower D-OCT. Simulation results confirm the wavelength dependency of D-OCT, with resolution variations having non-significant impact.
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Shumpei Fujimura, Ibrahim Abd El-Sadek, Pradipta Mukherjee, Yiheng Lim, Lida Zhu, Rion Morishita, Yuanke Feng, and Yoshiaki Yasuno "Wavelength and resolution dependency of dynamic optical coherence tomography", Proc. SPIE PC12854, Label-free Biomedical Imaging and Sensing (LBIS) 2024, PC128540D (13 March 2024); https://doi.org/10.1117/12.3001490
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KEYWORDS
Optical coherence tomography
Computing systems
Image resolution
Tissues
Breast cancer
Diffusion
Modeling
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