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Quantitative Oblique Back-Illumination Microscopy (qOBM) enables 3D quantitative phase imaging (QPI) in thick scattering samples. Recently, we developed a deep learning assisted single-capture qOBM (SC-qOBM) method to achieve fast quantitative phase tomography in vivo. This novel approach paves the way for a number of in-vivo applications that were previously out of reach for QPI. Here, we showcase two applications of SC-qOBM: (1) in-vivo imaging of blood flow in mouse brains for studying blood diseases and (2) non-invasive imaging of blood flow in humans for hematological and in-vivo flow cytometry analysis. This work highlights SC-qOBM’s potential in various biomedical applications.
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