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13 March 2024 Advancing esophageal dysplasia detection: clinical validation of a novel combined a/LCI and endoscopic OCT device
Evan T. Jelly, Haoran Zhang, Nicholas J. Shaheen M.D., Adam Wax
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Proceedings Volume PC12856, Biomedical Applications of Light Scattering XIV; PC1285601 (2024) https://doi.org/10.1117/12.3003302
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
In this presentation, we introduce a novel imaging system that combines optical coherence tomography (OCT) and angle-resolved low-coherence interferometry (a/LCI) for enhanced detection of esophageal dysplasia. By integrating wide area imaging with high-resolution OCT and depth-resolved a/LCI measurements, we aim to provide a sensitive and specific screening method. This innovative approach overcomes the limitations of traditional techniques and enables real-time imaging guidance for accurate coverage of at-risk tissue surfaces. Our pilot clinical study shows promising results, suggesting that this combined system holds great potential in improving early detection and diagnosis of esophageal dysplasia in patients at risk.
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Evan T. Jelly, Haoran Zhang, Nicholas J. Shaheen M.D., and Adam Wax "Advancing esophageal dysplasia detection: clinical validation of a novel combined a/LCI and endoscopic OCT device", Proc. SPIE PC12856, Biomedical Applications of Light Scattering XIV, PC1285601 (13 March 2024); https://doi.org/10.1117/12.3003302
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KEYWORDS
Optical coherence tomography
Endoscopy
Coherence imaging
Imaging systems
System integration
Tissues
Natural surfaces
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