Fluorescence enhancement with transient ultrasound light waveguiding

Maxim N. Cherkashin; Volodymyr Rohovets; Carsten Brenner; Georg Schmitz; Martin R Hofmann

doi:10.1117/12.3029596

19 June 2024 Fluorescence enhancement with transient ultrasound light waveguiding

Maxim N. Cherkashin, Volodymyr Rohovets, Carsten Brenner, Georg Schmitz, Martin R Hofmann

Proceedings Volume PC13010, Tissue Optics and Photonics III; PC130100I (2024) https://doi.org/10.1117/12.3029596
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

Ultrasound waveguiding of light is a recently introduced technique aiding light transport in scattering media, effectively reducing scattering strength. This technique locally, transiently, reversibly modifies the refractive index of the medium, recollecting and guiding some of the scattered photons to increase light intensity in depth. Here we use transient transversal ultrasound light waveguiding to increase the strength of the signal received from fluorescent target hidden behind a 3 mm thick scattering phantom. We use a common linear array transducer and transmission geometry and show waveguiding-induced increase of fluorescence, excited by a pulsed 532 nm light, typical for photoacoustic imaging setting.

Conference Presentation

Citation Download Citation

Maxim N. Cherkashin, Volodymyr Rohovets, Carsten Brenner, Georg Schmitz, and Martin R Hofmann "Fluorescence enhancement with transient ultrasound light waveguiding", Proc. SPIE PC13010, Tissue Optics and Photonics III, PC130100I (19 June 2024); https://doi.org/10.1117/12.3029596

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