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1 July 2009 Quantitative detection of chemical compounds in human hair with coherent anti-Stokes Raman scattering microscopy
Maxwell Zimmerley, Chia-Yu Lin, David C. Oertel, Jennifer M. Marsh, Jimmie L. Ward, Eric Olaf Potma
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Journal of Biomedical Optics, Vol. 14, Issue 4, 044019 (July 2009). https://doi.org/10.1117/1.3184444
Abstract
Coherent anti-Stokes Raman scattering (CARS) microscopy is used to determine the distribution and concentration of selected compounds in intact human hair. By generating images based on ratiometric CARS contrast, quantitative concentration maps of both water and externally applied d-glycine are produced in the cortex of human hair fibers. Both water and d-glycine are found to homogeneously distribute throughout the cortical regions of the hair. The ability to selectively detect molecular agents in hair fibers is of direct relevance to understanding the chemical and physical mechanisms that underlie the performance of hair-care products.
©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Maxwell Zimmerley, Chia-Yu Lin, David C. Oertel, Jennifer M. Marsh, Jimmie L. Ward, and Eric Olaf Potma "Quantitative detection of chemical compounds in human hair with coherent anti-Stokes Raman scattering microscopy," Journal of Biomedical Optics 14(4), 044019 (1 July 2009). https://doi.org/10.1117/1.3184444
Published: 1 July 2009
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Cited by 34 scholarly publications.
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KEYWORDS
Raman spectroscopy
Microscopy
Optical fibers
Water
Molecules
Calibration
CARS tomography
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