Breast cancer is the most common cancer, and early detection is important to improve survival rates. For diagnosis, new imaging modality are required. Photoacoustic imaging (PAI) is arguably the most exciting 3D molecular imaging technique, since it provides functional information on the hemoglobin distribution in breast that can be used to identify malignant lesions. PAI is an absorption technique where optical pulses are used to generate sound waves. It combines both the advantages of the high contrast of optical imaging and the deep penetration of acoustic imaging. We have developed an extreme sensitivity optomechanical ultrasound sensor. This sensor enables broadband, high-resolution PAI and present great future promise in advancing breast cancer screening.
Ultrafast 3D transesophageal echocardiographic (TEE) imaging, combined with 3D echo particle image velocimetry
(ePIV), would be ideal for tracking the complex blood flow patterns in the heart. We are developing a miniature pediatric
matrix TEE transducer that employs micro-beamforming (μBF) and allows high framerate in 3D. In this paper, we assess
the feasibility of 3D ePIV with a high frame rate, small aperture transducer and the influence of the micro-beamforming
technique. We compare the results of 3D ePIV on simulated images using the μBF transducer and an idealized, fully
sampled (FS) matrix transducer.
For the two transducers, we have simulated high-framerate imaging of an 8.4mm diameter artery having a known 4D
velocity field. The simulations were performed in FieldII. 1000 3D volumes, at a rate of 1000 volumes/sec, were created
using a single diverging transmission per volume. The error in the 3D velocity estimation was measured by comparing
the ePIV results of both transducers to the ground truth.
The results on the simulated volumes show that ePIV can estimate the 4D velocity field of the arterial phantom using
these small-aperture transducers suitable for pediatric 3D TEE. The μBF transducer (RMSE 44.0%) achieved
comparable ePIV accuracy to that of the FS transducer (RMSE 42.6%).
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.