Mr. Iman Kafian Attari Profile

Iman Kafian Attari

at Huawei Technologies

SPIE Involvement:

Author

Publications (2)

SPIE Journal Paper | 13 December 2023 Open Access

Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix

Iman Kafian-Attari, Ervin Nippolainen, Florian Bergmann, Akuroma George, Petri Paakkari, Arash Mirhashemi, Florian Foschum, Alwin Kienle, Juha Töyräs, Isaac O. Afara

JBO, Vol. 28, Issue 12, 125003, (December 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.12.125003

KEYWORDS: Cartilage, Tissues, Light scattering, Collagen, Rayleigh scattering, Scattering, Anatomy, Biological samples, Mie scattering, Transmittance

Read Abstract +

SignificanceArticular cartilage exhibits a zonal architecture, comprising three distinct zones: superficial, middle, and deep. Collagen fibers, being the main solid constituent of articular cartilage, exhibit unique angular and size distribution in articular cartilage zones. There is a gap in knowledge on how the unique properties of collagen fibers across articular cartilage zones affect the scattering properties of the tissue.AimThis study hypothesizes that the structural properties of articular cartilage zones affect its scattering parameters. We provide scattering coefficient and scattering anisotropy factor of articular cartilage zones in the spectral band of 400 to 1400 nm. We enumerate the differences and similarities of the scattering properties of articular cartilage zones and provide reasoning for these observations.ApproachWe utilized collimated transmittance and integrating sphere measurements to estimate the scattering coefficients of bovine articular cartilage zones and bulk tissue. We used the relationship between the scattering coefficients to estimate the scattering anisotropy factor. Polarized light microscopy was applied to estimate the depth-wise angular distribution of collagen fibers in bovine articular cartilage.ResultsWe report that the Rayleigh scatterers contribution to the scattering coefficients, the intensity of the light scattered by the Rayleigh and Mie scatterers, and the angular distribution of collagen fibers across tissue depth are the key parameters that affect the scattering properties of articular cartilage zones and bulk tissue. Our results indicate that in the short visible region, the superficial and middle zones of articular cartilage affect the scattering properties of the tissue, whereas in the far visible and near-infrared regions, the articular cartilage deep zone determines articular cartilage scattering properties.ConclusionThis study provides scattering properties of articular cartilage zones. Such findings support future research to utilize optical simulation to estimate the penetration depth, depth-origin, and pathlength of light in articular cartilage for optical diagnosis of the tissue.

DOWNLOAD PAPER

Proceedings Article | 5 May 2020 Paper

Optical properties of articular cartilage in the near-Infrared spectral range are related to its proteoglycan content

Iman Kafian-Attari, Dmitry Semenov, Ervin Nippolainen, Markku Hauta-Kasari, Juha Töyräs, Isaac Afara

Proceedings Volume 11363, 113630W (2020) https://doi.org/10.1117/12.2555291

KEYWORDS: Cartilage, Optical properties, Light scattering, Tissues, Bone, Natural surfaces, Tissue optics, Diffuse optical spectroscopy, Light-matter interactions, Laser tissue interaction, Near infrared spectroscopy, Chemometrics

Read Abstract +

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years