Hyperspectral imaging can reveal the slightest difference in the spectral response of seemingly identical inks. We have studied the reflectivity of the fundamental colors used in inkjet printers, and found distinctive spectral features depending on the supplier of the ink. We analysed discontinued bank notes, and identified discrepancies in the SWIR response of allegedly genuine notes of different ages. This may either reveal information on the history of the note as a legal tender, or reveal the fake nature of a note sold as genuine. These observations may be useful in the identification of high-fidelity counterfeit documents, or bank notes.
Hyperspectral imaging (HSI) is being shown as an emerging modality with a great potential in disease diagnosis and surgical cancer resection. Herein, we evaluate feasibility of the HSI to discriminate and diagnose colon cancer metastasis in a liver from five hematoxylin and eosin stained histopathological specimens. They were collected from the same patient during intraoperative frozen section analysis. Cancer and non-cancer spectra along with corresponding spatial maps were estimated from hyperspectral images by means of spectral unmixing. It was found that maximal angle between cancer spectra is 1.02 degrees less than minimal angle between cancer vs. non-cancer spectra. Thus, spectrum angle mapper was used for pixel-based diagnosis of cancer yielding sensitivity between 81.23% and 97.12%, specificity between 85.85% and 97.3%, and accuracy between 86.85% and 96.92%.
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