Optical coherence tomography (OCT) is a promising method of glial tumors borders diagnostics. Nowadays it is possible to use hand-held and microscope mounted OCT devices during tumor removal. But still there are no clearly visual assessment criteria of OCT images, on the basis of which good differentiation between glioma tissue and white matter can be performed. This paper presents such criteria for crosspolarization OCT (CP OCT), which can detect both the scattering and polarization properties of tissues.
In the case of infiltrative brain tumors the surgeon faces difficulties in determining their boundaries to achieve total resection. The aim of the investigation was to evaluate the performance of multimodal OCT (MM OCT) for differential diagnostics of normal brain tissue and glioma using an experimental model of glioblastoma. The spectral domain OCT device that was used for the study provides simultaneously two modes: cross-polarization and microangiographic OCT. The comparative analysis of the both OCT modalities images from tumorous and normal brain tissue areas concurrently with histologic correlation shows certain difference between when accordingly to morphological and microvascular tissue features.
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