Photoacoustic imaging (PAI) is an emerging medical imaging modality that provides high contrast and spatial resolution. A core unsolved problem to effectively support interventional healthcare is the accurate quantification of the optical tissue properties, such as the absorption and scattering coefficients. The contribution of this work is two-fold. We demonstrate the strong dependence of deep learning-based approaches on the chosen training data and we present a novel approach to generating simulated training data. According to initial in silico results, our method could serve as an important first step related to generating adequate training data for PAI applications.
Photoacoustic imaging (PAI) has the potential to revolutionize healthcare due to the valuable information on tissue physiology that is contained in multispectral signals. Clinical translation of the technology requires conversion of the high-dimensional acquired data into clinically relevant and interpretable information. In this work, we present a deep learning-based approach to semantic segmentation of multispectral PA images to facilitate interpretability of recorded images. Based on a validation study with experimentally acquired data of healthy human volunteers, we show that a combination of tissue segmentation, sO2 estimation, and uncertainty quantification can create powerful analyses and visualizations of multispectral photoacoustic images.
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