Dr. Saher M. Maswadi Profile

Dr. Saher M. Maswadi

Instructor at Univ of Texas Health Science Ctr at San Antonio

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Author

Publications (21)

Proceedings Article | 15 March 2016 Presentation + Paper

All-optical optoacoustic microscopy system based on probe beam deflection technique

Saher Maswadi, Dmitri Tsyboulskic, Caleb Roth, Randolph Glickman, Hope Beier, Alexander Oraevsky, Bennett Ibey

Proceedings Volume 9708, 970818 (2016) https://doi.org/10.1117/12.2217690

KEYWORDS: Laser beam diagnostics, Imaging systems, Microscopy, Acoustics, Adaptive optics, Sensors, Signal detection, Microscopes, Objectives, Image sensors, Tissue optics, Image resolution, Photodiodes

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Proceedings Article | 13 March 2014 Paper

Characterization of acoustic shockwaves generated by exposure to nanosecond electrical pulses

Caleb Roth, Saher Maswadi, Bennett Ibey, Hope Beier, Randolph Glickman

Proceedings Volume 8941, 89411O (2014) https://doi.org/10.1117/12.2042184

KEYWORDS: Acoustics, Electrodes, Laser beam diagnostics, Plasma, Tungsten, Sensors, Metals, Cavitation, Silver, Platinum

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Proceedings Article | 3 March 2014 Paper

Optoacoustic microscopy using laser beam deflection technique

E. Khachatryan, S. Maswadi, D. Tsyboulski, E. Barnes, D. Sardar, A. Oraevsky, K. Nash, R. Glickman

Proceedings Volume 8943, 89432T (2014) https://doi.org/10.1117/12.2040718

KEYWORDS: Laser beam diagnostics, Tissue optics, Ultrasonography, Acoustics, Microscopy, Objectives, Image resolution, Tissues, Transducers, Nanoparticles

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Optoacoustic microscopy (OAM) is an emerging technology combining the beneficial features of optical contrast and ultrasound resolution, to form a hybrid imaging technique capable of multi-scale, high-contrast and high-resolution imaging through optically scattering biological tissues. In the past 15 years, two system modifications have been developed for optoacoustic / photoacoustic microscopy: acoustic-resolution AR-OAM and optical-resolution OR-OAM. Typically, acoustic resolution systems can image deeper tissues structures, however, with resolution at least an order of magnitude worse than the systems of optical-resolution. It would be attractive for variety of biomedical applications to attain high (submicron) resolution at a depth exceeding the present limit of the optical resolution optoacoustic microscopy. Here we introduce a novel, all-optical method for OAM, in which not only thermal energy deposition, but also optoacoustic signal detection is achieved optically. In our design the probe laser beam was used as an ultrawide-band ultrasonic transducer. In this method the acoustic pressure wave amplitude is proportional to the angle of deflection of the probing CW laser beam incident on a balanced dual photodiode. Such laser beam deflection (LBD) method overcomes the limitations of conventional piezoelectric ultrasound transducers and optical interferometers. LBD method allows one to use high numerical aperture objectives for better focusing, avoid distortions associated with the system elements that separate optical and acoustic paths, and provides better sensitivity than any optical interferometer. It also provides a non-contact method that is insensitive to optical and acoustic artifacts typical of backward mode of optoacoustic imaging. The LBD sensitivity depends on a large number of system parameters such as probe beam power, spot size, interaction length, optical refraction index of the coupling medium, laser wavelength, photodiode sensitivity, proximity to the optoacoustic source, and thus, can be optimized. The basic setup of OR-LBD-OAM shows high sensitivity competitive with commercial ultrasonic transducers. We report first images of biological cells and tissues obtained using this technique.

Proceedings Article | 22 February 2013 Paper

Opto-acoustic characterization of chitosan based gold nanoparticles (GNPs) synthesized in the presence of monovalent salt

Samantha Franklin, Zannatul Yasmin, Saher Maswadi, Kelly Nash

Proceedings Volume 8595, 85951H (2013) https://doi.org/10.1117/12.2003124

KEYWORDS: Nanoparticles, Gold, Absorption, Ultraviolet radiation, Particles, Pulsed laser operation, Photoacoustic spectroscopy, Mirrors, Macromolecules, Sodium

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Proceedings Article | 15 February 2013 Paper

Detection of oxidative stress biomarker-induced assembly of gold nanoparticles in retinal pigment epithelial cells

Z. Yasmin, Y. Lee, S. Maswadi, R. Glickman, K. Nash

Proceedings Volume 8579, 85790E (2013) https://doi.org/10.1117/12.2003156

KEYWORDS: Gold, Nanoparticles, Absorption, Photoacoustic spectroscopy, Surface plasmons, Sensors, Biosensors, Scanning electron microscopy, Nanolithography, Biomedical optics

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Proceedings Article | 28 February 2011 Paper

Optoacoustic sensor for nanoparticle linked immunosorbent assay (NanoLISA)

André Conjusteau, Anton Liopo, Dmitri Tsyboulski, Sergey Ermilov, William Elliott, Norman Barsalou, Saher Maswadi, Randolph Glickman, Alexander Oraevsky

Proceedings Volume 7899, 789910 (2011) https://doi.org/10.1117/12.879401

KEYWORDS: Gold, Sensors, Nanoparticles, Biosensors, Target detection, Ferroelectric polymers, Pulsed laser operation, Acoustics, Signal to noise ratio, Nanorods

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Proceedings Article | 23 February 2011 Paper

Identification of radiolucent foreign bodies in tissue using optoacoustic spectroscopic imaging

Leland Page, Saher Maswadi, Randolph Glickman

Proceedings Volume 7899, 78993I (2011) https://doi.org/10.1117/12.875403

KEYWORDS: Absorption, Spectroscopy, Tissue optics, Laser beam diagnostics, Imaging spectroscopy, Optical parametric oscillators, Visible radiation, Absorption spectroscopy, Acoustics, Tissues

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Proceedings Article | 18 February 2011 Paper

Nano-LISA for in vitro diagnostic applications

Saher Maswadi, Randolph Glickman, Rowe Elliott, Norman Barsalou

Proceedings Volume 7899, 78991O (2011) https://doi.org/10.1117/12.874922

KEYWORDS: Gold, Laser beam diagnostics, Silver, In vitro testing, Target detection, Sensors, Signal detection, LabVIEW, Absorption, Nanorods

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Proceedings Article | 12 March 2010 Paper

Optoacoustic spectroscopic imaging of radiolucent foreign bodies

Leland Page, Saher Maswadi, Randolph Glickman

Proceedings Volume 7629, 76290E (2010) https://doi.org/10.1117/12.844468

KEYWORDS: Spectroscopy, Absorption, Imaging spectroscopy, Imaging systems, Laser beam diagnostics, Optical parametric oscillators, Tissues, Ultrasonography, Glasses, Visible radiation

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Proceedings Article | 25 February 2009 Paper

Detection of gold-nanorod targeted pathogens using optical and piezoelectric optoacoustic sensors: comparative study

André Conjusteau, Saher Maswadi, Sergey Ermilov, Hans-Peter Brecht, Norman Barsalou, Randolph Glickman, Alexander Oraevsky

Proceedings Volume 7177, 71771P (2009) https://doi.org/10.1117/12.813434

KEYWORDS: Transducers, Acoustics, Sensors, Laser beam diagnostics, Gold, Signal detection, Signal generators, Target detection, Pathogens, Nanorods

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Proceedings Article | 12 February 2009 Paper

Optoacoustic detection of viral antigens using targeted gold nanorods

Saher Maswadi, Lee Woodward, Randolph Glickman, Norman Barsalou

Proceedings Volume 7177, 71771Q (2009) https://doi.org/10.1117/12.809186

KEYWORDS: Gold, RGB color model, Silver, Target detection, Signal detection, Laser spectroscopy, Absorption, Laser beam diagnostics, Spectroscopy, Nanorods

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Proceedings Article | 12 February 2009 Paper

Optoacoustic imaging: application to the detection of foreign bodies

Leland Page, Saher Maswadi, Randolph Glickman, Norman Barsalou, Ron Branstetter, Scott Thompson

Proceedings Volume 7177, 71770X (2009) https://doi.org/10.1117/12.809516

KEYWORDS: Ultrasonography, Laser beam diagnostics, Acoustics, Imaging systems, Tissues, Transducers, Magnetic resonance imaging, Optical parametric oscillators, Image resolution, X-ray computed tomography

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Proceedings Article | 28 February 2008 Paper

Optoacoustic sensing of ocular bacterial antigen using targeted gold nanorods

Saher Maswadi, Leland Page, Lee Woodward, Randolph Glickman, Norman Barsalou

Proceedings Volume 6856, 685615 (2008) https://doi.org/10.1117/12.766512

KEYWORDS: Silver, Gold, Optical parametric oscillators, Target detection, Absorption, Spectroscopy, Signal detection, Laser spectroscopy, Laser beam diagnostics, Nanorods

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Proceedings Article | 13 February 2007 Paper

Investigational detection of pharmacological agents in the eye using photoacoustic spectroscopy

Saher Maswadi, Randolph Glickman, Norman Barslou, Rowe Elliott

Proceedings Volume 6437, 643706 (2007) https://doi.org/10.1117/12.699094

KEYWORDS: Photoacoustic spectroscopy, Eye, Tissue optics, Absorption, Optical parametric oscillators, Pulsed laser operation, In vivo imaging, Laser tissue interaction, Tunable lasers, Retina

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Proceedings Article | 7 March 2006 Paper

Investigation of photoacoustic spectroscopy for biomolecular detection

Saher Maswadi, Randolph Glickman, Norman Barsalou, Rowe Elliott

Proceedings Volume 6138, 61380V (2006) https://doi.org/10.1117/12.674408

KEYWORDS: Photoacoustic spectroscopy, Eye, Tissue optics, In vivo imaging, Absorption, Laser beam diagnostics, Pulsed laser operation, Retina, Continuous wave operation, Q switched lasers

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Proceedings Article | 15 April 2005 Paper

Intracellular signaling mechanisms responsive to laser-induced photochemical and thermal stress

Randolph Glickman, Mohan Natarajan, Benjamin Rockwell, Michael Denton, Saher Maswadi, Neeru Kumar, Francis Nieves-Roldan

Proceedings Volume 5695, (2005) https://doi.org/10.1117/12.584135

KEYWORDS: Continuous wave operation, Proteins, Cell death, Laser tissue interaction, Injuries, Ultraviolet radiation, Oxygen, Receptors, Laser therapeutics, Oxidation

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SPIE Journal Paper | 1 July 2004 Open Access

Temperature mapping of laser-induced hyperthermia in an ocular phantom using magnetic resonance thermography

Saher Maswadi, Stephen Dodd, Jia Hong Gao, Randolph Glickman

JBO, Vol. 9, Issue 04, (July 2004) https://doi.org/10.1117/12.10.1117/1.1751399

KEYWORDS: Temperature metrology, Magnetism, Thermography, Thermal modeling, Eye, Magnetic resonance imaging, Spatial resolution, Laser tissue interaction, Laser therapeutics, Laser scattering

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Proceedings Article | 1 July 2004 Paper

Noninvasive thermography of laser-induced hyperthermia using magnetic resonance

Saher Maswadi, Randolph Glickman, Stephen Dodd, Jia Hong Gao

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.527809

KEYWORDS: Temperature metrology, Laser tissue interaction, Thermal modeling, Magnetic resonance imaging, Laser scattering, Laser therapeutics, Spatial resolution, Diffusion, Thermography, Magnetism

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Proceedings Article | 15 April 2003 Paper

F2-laser applications for machining optoelectronic microstructures

Peter Dyer, Anne-Marie Johnson, Saher Maswadi, Christopher Walton

Proceedings Volume 4941, (2003) https://doi.org/10.1117/12.468388

KEYWORDS: Polymethylmethacrylate, Laser ablation, Vacuum ultraviolet, Fiber Bragg gratings, Etching, Absorption, Pulsed laser operation, Optoelectronics, Laser applications, Laser processing

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Proceedings Article | 13 September 2002 Paper

Interaction of VUV F2 laser radiation with glasses

Peter Dyer, Saher Maswadi, Christopher Walton

Proceedings Volume 4760, (2002) https://doi.org/10.1117/12.482072

KEYWORDS: Glasses, Laser ablation, Vacuum ultraviolet, Etching, Laser beam diagnostics, Absorption, Scanning electron microscopy, Laser damage threshold, Spatial resolution, Pulsed laser operation

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Proceedings Article | 18 June 2002 Paper

Glass micromachining using the VUV F2 laser

Peter Dyer, Saher Maswadi, Howard Snelling, Christopher Walton

Proceedings Volume 4637, (2002) https://doi.org/10.1117/12.470626

KEYWORDS: Glasses, Laser ablation, Polymethylmethacrylate, Absorption, Vacuum ultraviolet, Micromachining, Pulsed laser operation, Laser beam diagnostics, Atomic force microscopy, Laser damage threshold

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Showing 5 of 21 publications

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