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Furthermore, we use a waveguide to efficiently excite fluorescence or Raman active molecules drop casted as the top cladding of the waveguides. A fraction of the isotopically emitted fluorescence or Raman signal couples back to waveguide and rest is emitted normal to the surface. We discuss the theoretical efficiencies of both the methods of collection and compare it with the conventional microscope-based spectroscopic system. Waveguide based spectroscopic sensing offers higher efficiency due to increased light-matter interaction along the length of the waveguide. We presented detailed design, simulation, and experimental demonstration of grating coupler waveguide system suitable for son-chip spectroscopy application.
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