SignificanceGlaucoma, a leading cause of global blindness, disproportionately affects low-income regions due to expensive diagnostic methods. Affordable intraocular pressure (IOP) measurement is crucial for early detection, especially in low- and middle-income countries.AimWe developed a remote photonic IOP biomonitoring method by deep learning of the speckle patterns reflected from an eye sclera stimulated by a sound source. We aimed to achieve precise IOP measurements.ApproachIOP was artificially raised in 24 pig eyeballs, considered similar to human eyes, to apply our biomonitoring method. By deep learning of the speckle pattern videos, we analyzed the data for accurate IOP determination.ResultsOur method demonstrated the possibility of high-precision IOP measurements. Deep learning effectively analyzed the speckle patterns, enabling accurate IOP determination, with the potential for global use.ConclusionsThe novel, affordable, and accurate remote photonic IOP biomonitoring method for glaucoma diagnosis, tested on pig eyes, shows promising results. Leveraging deep learning and speckle pattern analysis, together with the development of a prototype for human eyes testing, could enhance diagnosis and management, particularly in resource-constrained settings worldwide.
In this presentation we will present two types of sensors for detecting SARS-CoV-2 symptoms. The first part of the presentation will address a contact-free sensor while its operation principle involves illuminating the inspected subject with a laser beam and analyzing with artificial intelligence (AI) based algorithms, the temporal-spatial changes occurring in the back scattered secondary 2D speckle patterns captured through properly defocused optics. The sensing is performed from a distance of several meters away and is applied to different regions of the subject’s body. We demonstrate measurements performed from the chest and then we extract various cardio-pulmonary bio-sign (several simultaneously) including the sounds of subject’s heart and lungs (like a remote stethoscope). We also perform measurements from the sclera and search for anomalies in the random eye movements. From those anomalies we estimate amount of saturated oxygen in the blood stream. All of the above-mentioned bio-parameters could be useful for remote early detection of SARS-CoV-2 symptoms. The AI algorithms are applied not only to extract the various bio-signs but also to perform the bio-medical diagnosis.
In the second part of the presentation, we will present fiber based sensor that is incorporated into textile and clothing and make them a smart-clothing capable via a non-tight contact way to perform sensing of various vital bio-signs (several simultaneously). The bio-parameters to be sensed are related to cardio-pulmonary activity as well as blood-pressure and thus could be associated with early detection of SARS-CoV-2 symptoms. The fiber sensor is based on enhanced multi-mode fiber while at its output an artificial intelligence (AI) based algorithm analyses the temporal-spatial characterizations of the generated dynamic 2D speckle patterns. The fiber sensors are positioned in several locations in the clothing and can perform the bio-measurement from different organs of the wearer and thus allow a comparative measurement which could assist in obtaining more agnostic and more reliable bio-sensing. The AI algorithms are applied not only to extract the various bio-signs but also to perform the bio-medical diagnosis.
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