Studies on dielectrophoretic separation using biochips with different electrode shapes

Yonghong Liu; Zhan Zhao; Jing Xu; Cheng Pang; Zhen Fang; Lidong Du

doi:10.1117/12.807033

2 February 2009 Studies on dielectrophoretic separation using biochips with different electrode shapes

Yonghong Liu, Zhan Zhao, Jing Xu, Cheng Pang, Zhen Fang, Lidong Du

Proceedings Volume 7159, 2008 International Conference on Optical Instruments and Technology: MEMS/NEMS Technology and Applications; 71590E (2009) https://doi.org/10.1117/12.807033
Event: International Conference of Optical Instrument and Technology, 2008, Beijing, China

Abstract

Dielectrophoresis (DEP) is a promising method for the automated separation of biological cells in a miniaturized format. This technology allows cells to be manipulated electronically while suspended in a microfluidic channel embedded in a silicon lab-on-chip. Different dielectrophoretic configurations have been designed and fabricated using micro-electro-mechanical- systems (MEMS) technology, which are investigated comparatively on their function principles and separation efficiencies. DEP responses of colloidal polystyrene particles with the diameters of 10.9µm and 21.3µm suspended in deionized water are measured. It is found that, at the low medium conductivities used, global or local extreme points of electric fields can be configurated dependent on shapes and geometry sizes of electrodes. In addition, all the new phenomena appeared during whole experiment are observed, which may provide novel methods to separate micro particles.

Citation Download Citation

Yonghong Liu, Zhan Zhao, Jing Xu, Cheng Pang, Zhen Fang, and Lidong Du "Studies on dielectrophoretic separation using biochips with different electrode shapes", Proc. SPIE 7159, 2008 International Conference on Optical Instruments and Technology: MEMS/NEMS Technology and Applications, 71590E (2 February 2009); https://doi.org/10.1117/12.807033

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