Breast cancer is the most common cancer worldwide. Mammography screening and biopsy procedures for abnormal mammograms are the gold standard detection method, however, it is invasive, time-consuming, and labor-intensive. RNA biomarkers in circulating blood may be an alternative to the gold standard. We have adopted a multi-modal approach using Fourier transform infrared (FTIR) spectroscopy and Raman spectroscopy that provides a complete characterization of RNA biomarker fingerprints in the full spectrum. We have measured 99 patients’ serum samples and achieved a higher accuracy, specificity, and sensitivity using the multi-modal approach combined with machine learning analysis than using the individual techniques alone.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.