Iatrogenic nerve injuries often occur during surgical procedures yielding high morbidity. Numerous optical techniques are being investigated to provide nerve visualization and monitoring to both avoid and detect nerve injury. However, there is insufficient VIS-IR optical properties data for nerve and surrounding tissues, to facilitate needed advancements in the biophotonic approaches being developed for deployment. To fill this gap, we determined the absorption and reduced scattering coefficients of ex vivo nerve, muscle, tendon, and adipose tissues from four rats and human cadavers between 350-2500nm. The results provide valuable insights for optimizing the optical contrast of nerves for improved surgical guidance.
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