A lead selenide (PbSe) NC-based phototransistor memory (PTM), wherein graphene oxide (GO) sheets covered by Au nanoparticles (NCs) act as double charge trapping layers, is studied under near-infrared (NIR) light. The memory window (ΔV_th) can be significantly enlarged by light-assisted programming and erasing processes, wherein the photogenerated carriers in a PbSe NCs channel can be trapped and detrapped by the GO/Au NCs charge-trapping layers. The PTM achieved an enhanced ΔV_th from 0.7 V in the dark to 1.8 V under the NIR light, due to the increasing number of photogenerated charges due to the NIR light. The PTM exhibited high responsivity (R), external quantum efficiency (EQE), and detectivity (D  *  ) of about 13.9  A  /  W, 2.2  ×  10³  %  , and 1.5  ×  10⁸ Jones, respectively. Due to the good photoresponsibility of the PbSe NCs, the PTM exhibited a large ΔV_th under low programming/erasing voltages under the NIR light and realized multilevel memory. The results presented on photoassisted memory may pave a way to large-area, flexible, low-temperature fabrication, and photoreactive memory devices.