Prof. Antonio Pifferi Profile

Prof. Antonio Pifferi

Full Professor at Politecnico di Milano

SPIE Involvement:

Conference Program Committee | Author

Publications (188)

SPIE Journal Paper | 11 June 2024 Open Access

Tutorial on methods for estimation of optical absorption and scattering properties of tissue

Ran Tao, Janek Gröhl, Lina Hacker, Antonio Pifferi, Darren Roblyer, Sarah E. Bohndiek

JBO, Vol. 29, Issue 06, 060801, (June 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.6.060801

KEYWORDS: Tissues, Scattering, Optical properties, Absorption, Tissue optics, Signal detection, Diffusion, Light scattering, Light sources and illumination, Light absorption

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Proceedings Article | 13 March 2024 Presentation

Bioresorbable multifunctional fiber-optic devices for theranostic and monitoring of tumor

Jawad Pandayil, Nadia Boetti, Lorenzo Cortese, Vamshi Damagatla, Davide Janner, Turgut Durduran, Antonio Pifferi, Diego Pugliese

Proceedings Volume PC12835, PC1283503 (2024) https://doi.org/10.1117/12.3002672

KEYWORDS: Fiber optics, Tumors, Tissues, Photodynamic therapy, Phosphates, Optical fibers, Calcium, Biomedical applications, Surgery, Spectroscopes

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Proceedings Article | 8 September 2023 Paper

Use of bioresorbable fibers for interstitial time-domain diffuse optical spectroscopy with fast-gating

Vamshi Damagatla, Nadia Boetti, Laura Di Sieno, Diego Pugliese, Davide Janner, Alberto Dalla Mora, Antonio Pifferi

Proceedings Volume 12628, 1262818 (2023) https://doi.org/10.1117/12.2670504

KEYWORDS: Absorption, Diffuse optical spectroscopy, Single photon avalanche diodes, Scattering, Liquids, Tissues, Optical fibers, Light scattering, Glasses, Water

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Proceedings Article | 9 August 2023 Paper

Reconstruction of Raman spectra of two-layer diffusive media: model-based approach in time-domain

Stefan Šušnjar, Fabrizio Martelli, Johannes Swartling, Nina Reistad, Antonio Pifferi

Proceedings Volume 12628, 126280R (2023) https://doi.org/10.1117/12.2670807

KEYWORDS: Raman spectroscopy, Photons, Model-based design, Reflectivity, Raman scattering, Emission wavelengths, Simulations, Matrices, Mathematical modeling, Tissues

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Proceedings Article | 9 August 2023 Paper

Evaluation of neoadjuvant chemotherapy-induced changes in contralateral healthy breast tissue through diffuse optical spectroscopy

Nikhitha Mule, Giulia Maffeis, Carolina Santangelo, Rinaldo Cubeddu, Antonio Pifferi, Pietro Panizza, Paola Taroni

Proceedings Volume 12628, 1262808 (2023) https://doi.org/10.1117/12.2670661

KEYWORDS: Tissues, Breast, Diffuse optical spectroscopy, Chemotherapy, Breast cancer, Tumors, Tissue optics, Spectral response, Optical imaging, Mammography

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Proceedings Article | 9 August 2023 Paper

Initial examples of the SOLUS multimodal potential

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M. Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, P. Taroni

Proceedings Volume 12628, 1262807 (2023) https://doi.org/10.1117/12.2670430

KEYWORDS: Radio optics, Machine learning, Data processing, Absorption, Ultrasonography, Multimodal imaging, Elastography, Doppler tomography, Diffuse optical tomography, Critical dimension metrology

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SPIE Journal Paper | 3 April 2023 Open Access

Interstitial null-distance time-domain diffuse optical spectroscopy using a superconducting nanowire detector

Vamshi Damagatla, Pranav Lanka, Annalisa Brodu, Niels Noordzij, Jessie Qin-Dregely, Andrea Farina, Antonio Pifferi

JBO, Vol. 28, Issue 12, 121202, (April 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.12.121202

KEYWORDS: Photons, Simulations, Absorption, Diffuse optical spectroscopy, Light absorption, Scattering, Liquids, Superconductors, Signal detection, Nanowires

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SignificanceInterstitial fiber-based spectroscopy is gaining interest for real-time in vivo optical biopsies, endoscopic interventions, and local monitoring of therapy. Different from other photonics approaches, time-domain diffuse optical spectroscopy (TD-DOS) can probe the tissue at a few cm distance from the fiber tip and disentangle absorption from the scattering properties. Nevertheless, the signal detected at a short distance from the source is strongly dominated by the photons arriving early at the detector, thus hampering the possibility of resolving late photons, which are rich in information about depth and absorption.AimTo fully benefit from the null-distance approach, a detector with an extremely high dynamic range is required to effectively collect the late photons; the goal of our paper is to test its feasibility to perform TD-DOS measurements at null source–detector separations (NSDS).ApproachIn particular, we demonstrate the use of a superconducting nanowire single photon detector (SNSPD) to perform TD-DOS at almost NSDS ( ≈ 150 μm ) by exploiting the high dynamic range and temporal resolution of the SNSPD to extract late arriving, deep-traveling photons from the burst of early photons.ResultsThis approach was demonstrated both on Monte Carlo simulations and on phantom measurements, achieving an accuracy in the retrieval of the water spectrum of better than 15%, spanning almost two decades of absorption change in the 700- to 1100-nm range. Additionally, we show that, for interstitial measurements at null source–detector distance, the scattering coefficient has a negligible effect on late photons, easing the retrieval of the absorption coefficient.ConclusionsUtilizing the SNSPD, broadband TD-DOS measurements were performed to successfully retrieve the absorption spectra of the liquid phantoms. Although the SNSPD has certain drawbacks for use in a clinical system, it is an emerging field with research progressing rapidly, and this makes the SNSPD a viable option and a good solution for future research in needle guided time-domain interstitial fiber spectroscopy.

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Proceedings Article | 7 March 2023 Presentation + Paper

Superconducting nanowire detector for interstitial null-separation time-domain diffuse optical spectroscopy

Vamshi Damagatla, Pranav Lanka, Andrea Farina, Annalisa Brodu, Niels Noordzijc, Jessie Qin-Dregely, Antonio Pifferi

Proceedings Volume 12376, 123760F (2023) https://doi.org/10.1117/12.2649028

KEYWORDS: Photons, Monte Carlo methods, Absorption, Superconductors, Nanowires, Simulations, Diffuse optical spectroscopy, Silicon photomultipliers, Scattering

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Proceedings Article | 7 March 2023 Presentation + Paper

Temporal evolution of optical properties at different temperatures of biological tissues

Alessandro Bossi, Leonardo Bianchi, Paola Saccomandi, Antonio Giovanni Pifferi

Proceedings Volume 12376, 123760M (2023) https://doi.org/10.1117/12.2649110

KEYWORDS: Optical properties, Tissues, Proteins, Absorption, Collagen, Scattering, Photons, Optical sensing, Muscles, Single photon detectors

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Proceedings Article | 7 March 2023 Presentation + Paper

Breast lesion classification based on absorption and composition parameters: a look at SOLUS first outcomes

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, Paola Taroni

Proceedings Volume 12376, 123760K (2023) https://doi.org/10.1117/12.2648945

KEYWORDS: Breast, Absorption, Machine learning, Image segmentation, Diffuse optical tomography, Diffuse optical imaging, Data analysis, Breast cancer, Ultrasound transducers

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Proceedings Article | 7 March 2023 Presentation + Paper

Monitoring neoadjuvant chemotherapy through time domain diffuse optical spectroscopy: preliminary clinical results

Nikhitha Mule, Giulia Maffeis, Carolina Santangelo, Rinaldo Cubeddu, Antonio Pifferi, Pietro Panizza, Paola Taroni

Proceedings Volume 12376, 123760L (2023) https://doi.org/10.1117/12.2648865

KEYWORDS: Breast, Tumors, Collagen, Tissues, Chemotherapy, Breast cancer, Optical sensing, Imaging spectroscopy, Diffuse optical spectroscopy, Diffuse optical imaging

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SPIE Journal Paper | 30 August 2022 Open Access

Optical imaging and spectroscopy for the study of the human brain: status report

Hasan Ayaz, Wesley Baker, Giles Blaney, David Boas, Heather Bortfeld, Kenneth Brady, Joshua Brake, Sabrina Brigadoi, Erin M. Buckley, Stefan Carp, Robert Cooper, Kyle Cowdrick, Joseph Culver, Ippeita Dan, Hamid Dehghani, Anna Devor, Turgut Durduran, Adam Eggebrecht, Lauren Emberson, Qianqian Fang, Sergio Fantini, Maria Angela Franceschini, Jonas Fischer, Judit Gervain, Joy Hirsch, Keum-Shik Hong, Roarke Horstmeyer, Jana Kainerstorfer, Tiffany Ko, Daniel Licht, Adam Liebert, Robert Luke, Jennifer Lynch, Jaume Mesquida, Rickson Mesquita, Noman Naseer, Sergio Novi, Felipe Orihuela-Espina, Thomas O'Sullivan, Darcy Peterka, Antonio Pifferi, Luca Pollonini, Angelo Sassaroli, João Ricardo Sato, Felix Scholkmann, Lorenzo Spinelli, Vivek Srinivasan, Keith St. Lawrence, Ilias Tachtsidis, Yunjie Tong, Alessandro Torricelli, Tara Urner, Heidrun Wabnitz, Martin Wolf, Ursula Wolf, Shiqi Xu, Changhuei Yang, Arjun Yodh, Meryem Yücel, Wenjun Zhou

NPh, Vol. 9, Issue S2, S24001, (August 2022) https://doi.org/10.1117/12.10.1117/1.NPh.9.S2.S24001

KEYWORDS: Brain, Near infrared spectroscopy, Neuroimaging, Imaging spectroscopy, Sensors, Optical imaging, Optical spectroscopy imaging, Optical spectroscopy, Spectroscopy, Tissue optics

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SPIE Journal Paper | 15 June 2022 Open Access

Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Michał Kacprzak, Piotr Sawosz, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu-Venkata-Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Lorenzo Frabasile, Pietro Levoni, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alberto Tosi, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

JBO, Vol. 27, Issue 07, 074716, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074716

KEYWORDS: Raster graphics, Optical properties, Diffuse optical imaging, Scattering, Imaging spectroscopy, Absorption, Tissue optics, Spectroscopes, Sensors, Oximetry

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SPIE Journal Paper | 24 March 2022 Open Access

Evaluation of a pipeline for simulation, reconstruction, and classification in ultrasound-aided diffuse optical tomography of breast tumors

Giuseppe Di Sciacca, Giulia Maffeis, Andrea Farina, Alberto Dalla Mora, Antonio Pifferi, Paola Taroni, Simon Arridge

JBO, Vol. 27, Issue 03, 036003, (March 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.3.036003

KEYWORDS: Tissues, Breast, Acoustics, Absorption, Tissue optics, Ultrasonography, Scattering, Image segmentation, Computer simulations, Diffuse optical tomography

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Proceedings Article | 7 March 2022 Presentation

Multimodal hybrid diffuse optics and ultrasound for screening for thyroid cancer

Pablo Fernández Esteberena, Gloria Aranda, Mauro Buttafava, Davide Contini, Lorenzo Cortese, Alberto Dalla Mora, Hamid Dehghani, Sixte de Fraguier, Felicia Hanzu, Giuseppe Lo Presti, Mireia Mora, An Nguyen Dinh, Antonio Pifferi, Marco Renna, Bogdan Rosinsky, Sabina Ruiz Janer, Mattia Squarcia, Paola Taroni, Alberto Tosi, Udo Weigel, Stanislaw Wojtkiewicz, Marta Zanoletti, Lisa Kobayashi Frisk, Turgut Durduran

Proceedings Volume PC11952, PC119520A (2022) https://doi.org/10.1117/12.2608941

KEYWORDS: Cancer, Ultrasonography, Diffuse optical imaging, Oxygen, Imaging systems, Diagnostics, Tumor growth modeling, Tissues, Tissue optics, Time resolved spectroscopy

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Proceedings Article | 2 March 2022 Presentation + Paper

Performance and reproducibility assessment across multiple time-domain near-infrared spectroscopy device replicas

M. Lacerenza, A. Torricelli, A. Tosi, D. Contini, A. Dalla Mora, A. Pifferi, F. Zappa, M. Buttafava

Proceedings Volume 11951, 1195108 (2022) https://doi.org/10.1117/12.2609404

KEYWORDS: Tissue optics, Near infrared spectroscopy, Picosecond phenomena, Scattering, Photons, Absorption, Manufacturing, Hemodynamics, Tissues, Standards development, Accuracy assessment

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Proceedings Article | 2 March 2022 Presentation

Characterization of picosecond laser modules for time-domain diffuse correlation spectroscopy application

Saeed Samaei, Lorenzo Colombo, Dawid Borycki, Marco Pagliazzi, Turgut Durduran, Piotr Sawosz, Stanislaw Wojtkiewicz, Davide Contini, Alessandro Torricelli, Antonio Pifferi, Adam Liebert

Proceedings Volume PC11959, PC119590B (2022) https://doi.org/10.1117/12.2609557

KEYWORDS: Picosecond phenomena, Spectroscopy, Spectroscopes, Laser sources, Blood circulation, Temporal coherence, Scattering, Pulsed laser operation, Liquids, Light scattering

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SPIE Journal Paper | 2 February 2022 Open Access

Reproducibility of identical solid phantoms

Fangzhou Zhao, Pietro Levoni, Lorenzo Frabasile, Hong Qi, Michele Lacerenza, Pranav Lanka, Alessandro Torricelli, Antonio Pifferi, Rinaldo Cubeddu, Lorenzo Spinelli

JBO, Vol. 27, Issue 07, 074713, (February 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074713

KEYWORDS: Scattering, Silicon, Absorption, Solids, Optical properties, Picosecond phenomena, Near infrared spectroscopy, Epoxies, Diffuse optical imaging, Visible radiation

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Proceedings Article | 9 December 2021 Paper

Phantoms for performance verification and quality control in developing a photonics-based medical device (VASCOVID): a regulatory driven approach

Sanathana Konugolu Venkata Sekar, Claudia Nunzia Guadagno, Marta Zanoletti, Lorenzo Cortese, Marco Pagliazzi, Pranav Lanka, Rainer Rothe Munoz, Eduardo Garrido, Talyta Carteano, Michele Lacerenza, Mauro Buttafava, Shahrzad Parsa, Udo Weigel, Alessandro Torricelli, Antonio Pifferi, Davide Contini, Turgut Durduran, Stefan Andersson-Engels

Proceedings Volume 11920, 119201Q (2021) https://doi.org/10.1117/12.2615398

KEYWORDS: Control systems, Manufacturing, Biomedical optics, Standards development, Solids, Liquids, Surveillance, Medical device development, Photonic devices, Optics manufacturing

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Proceedings Article | 9 December 2021 Paper

Motor cortex hemodynamic response function in freely moving subjects recorded via time domain fNIRS

Michele Lacerenza, Mauro Buttafava, Lorenzo Spinelli, Alberto Tosi, Alberto Dalla Mora, Franco Zappa, Antonio Pifferi, Bruno Cozzi, Alessandro Torricelli, Davide Contini

Proceedings Volume 11920, 1192018 (2021) https://doi.org/10.1117/12.2615350

KEYWORDS: Hemodynamics, Human subjects, Brain activation, Brain, Tissue optics, Solids, Scattering, Near infrared spectroscopy, Laser scattering, Functional magnetic resonance imaging

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Proceedings Article | 9 December 2021 Paper

SOLUS: a novel multimodal approach to ultrasound and diffuse optics imaging of breast cancer

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Giulia Maffeis, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Hélène Sportouche, Christophe Fraschini, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Proceedings Volume 11920, 1192003 (2021) https://doi.org/10.1117/12.2614309

KEYWORDS: Tissues, Picosecond phenomena, Imaging systems, Ultrasonography, Diffuse optical imaging, Breast cancer, Mammography, Sensors, Multimodal imaging, Breast

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Proceedings Article | 9 December 2021 Paper

Optical mammography in the time domain up to 1060 nm: from tests on healthy women to initial data for monitoring neoadjuvant chemotherapy

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Rinaldo Cubeddu, Antonio Pifferi, Carolina Santangelo, Pietro Panizza, Paola Taroni

Proceedings Volume 11920, 119200O (2021) https://doi.org/10.1117/12.2615236

KEYWORDS: Breast, Tumors, Collagen, Therapeutics, In vivo imaging, Oxygen, Optical testing, Mammography, Clinical trials, Signal processing

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Proceedings Article | 9 December 2021 Paper

Potential for improved thyroid cancer screening aided by multi-modal clinical ultrasound and hybrid diffuse optics (LUCA platform)

Pablo Fernandez Esteberena, G. Aranda, M. Buttafava, D. Contini, L. Cortese, A. Dalla Mora, H. Dehghani, S. de Fraguier, F. Hanzu, G. Lo Presti, M. Mora Porta, A. Nguyen-Dihn, A. Pifferi, M. Renna, B. Rosinski, S. Ruiz Janer, M. Squarcia, P. Taroni, A. Tosi, U. Weigel, S. Wojtkiewicz, M. Zanoletti, T. Durduran

Proceedings Volume 11920, 119200P (2021) https://doi.org/10.1117/12.2615237

KEYWORDS: Cancer, Ultrasonography, Tumor growth modeling, Tissues, Diffuse optical imaging, Near infrared spectroscopy, Hemodynamics, Neck, Diffusion, Blood circulation

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Proceedings Article | 9 December 2021 Paper

Fast-gated digital silicon photomultiplier maximizes light harvesting and depth sensitivity in time-domain diffuse optics

Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Enrico Conca, Vincenzo Sesta, Mauro Buttafava, Federica Villa, Franco Zappa, Davide Contini, Alessandro Torricelli, Paola Taroni, Alberto Tosi, Antonio Pifferi

Proceedings Volume 11920, 1192004 (2021) https://doi.org/10.1117/12.2614311

KEYWORDS: Photons, Light harvesting, Silicon photomultipliers, Diffuse optical imaging, Sensors, In vivo imaging, Digital photography, Optical signal processing, Picosecond phenomena, Tissues

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Proceedings Article | 9 December 2021 Paper

In-vivo time-domain diffuse correlation spectroscopy with a superconducting nanowire single-photon detector

L. Colombo, P. Lanka, A. Brodu, N. Noordzij, M. Pagliazzi, V. Parfentyeva, T. Durduran, A. Pifferi

Proceedings Volume 11920, 1192002 (2021) https://doi.org/10.1117/12.2614302

KEYWORDS: In vivo imaging, Single photon detectors, Superconductors, Nanowires, Spectroscopy, Signal to noise ratio, Sensors, Picosecond phenomena, Liquids, Tissues

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Proceedings Article | 5 March 2021 Presentation

A standardized approach to validate solid phantom recipes for 3D anthropomorphic phantoms in biophotonics

Sanathana Konugolu Venkata Sekar, Treasa Jiang, Pranav Lanka, Claudia Nunzia Guadagno, Andrea Pacheco, Antonio Pifferi, Stefan Andersson-Engels

Proceedings Volume 11633, 1163307 (2021) https://doi.org/10.1117/12.2579257

KEYWORDS: Biophotonic applications, 3D imaging standards, Solids, Tissue optics, Optical properties, Standards development, Tissues, Spectroscopy, Scattering

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Proceedings Article | 5 March 2021 Presentation + Paper

Investigating the lung using time-resolved diffuse optics

Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Pranav Lanka, Sanathana Konugolu Venkata Sekar, Massimo Miniati, Paola Taroni

Proceedings Volume 11639, 116390M (2021) https://doi.org/10.1117/12.2578858

KEYWORDS: Lung, Diffuse optical imaging, Signal detection, Optical properties, Monte Carlo methods, Chest, Silicon photomultipliers, Sensors, Pulsed laser operation, Physiology

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Proceedings Article | 5 March 2021 Presentation + Paper

In vivo time-domain diffuse correlation spectroscopy at 1 μm

L. Colombo, M. Pagliazzi, S. Konugolu-Venkata-Sekar, D. Contini, T. Durduran, A. Pifferi

Proceedings Volume 11639, 1163911 (2021) https://doi.org/10.1117/12.2578443

KEYWORDS: In vivo imaging, Spectroscopy, Light sources, Tissues, Tissue optics, Speckle, Signal to noise ratio, Particles, Liquids

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Proceedings Article | 5 March 2021 Presentation + Paper

A multi-laboratory comparison of photon migration instruments and their performances: the BitMap exercise

Sri Rama Pranav Kumar Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Giuseppe Lo Presti, Lorenzo Cortese, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Piotr Sawosz, Michal Kacprzak, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu Venkata Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Alessandro Torricelli, Alberto Tosi, Paola Taroni, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11639, 116390F (2021) https://doi.org/10.1117/12.2578521

KEYWORDS: Raster graphics, Photonic devices, Tissue optics, Spectroscopes, Oximetry, Optical components, Mammography, Imaging spectroscopy, Functional imaging

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Proceedings Article | 5 March 2021 Presentation + Paper

High-throughput multi-wavelength time-resolved optical mammograph: importance of in vivo performance assessment

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Rinaldo Cubeddu, Antonio Pifferi, Paola Taroni

Proceedings Volume 11639, 1163908 (2021) https://doi.org/10.1117/12.2577516

KEYWORDS: In vivo imaging, Collagen, Stray light, Silicon photomultipliers, Optical properties, New and emerging technologies, Infrared radiation, Clinical trials, Breast, Absorption

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Proceedings Article | 5 March 2021 Presentation + Paper

Auto-correlation for multi-view deconvolved reconstruction in light sheet microscopy

Daniele Ancora, Gianluca Valentini, Antonio Giovanni Pifferi, Andrea Bassi

Proceedings Volume 11649, 116490X (2021) https://doi.org/10.1117/12.2583004

KEYWORDS: Microscopy, Tomography, Reconstruction algorithms, Algorithm development, Spatial resolution, Microscopes, Inspection, Fluorescent markers, Deconvolution, Biology

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Proceedings Article | 5 March 2021 Presentation + Paper

Broadband optical spectroscopy of the human adipose and muscle tissues: an in-vivo pilot study

Sri Rama Pranav Kumar Lanka, A. Segala, Andrea Farina, Paola Taroni, A. Valerio, E. Nisoli, Rinaldo Cubeddu, Antonio Pifferi

Proceedings Volume 11639, 116390I (2021) https://doi.org/10.1117/12.2578276

KEYWORDS: Tissues, In vivo imaging, Optical spectroscopy, Optical properties, Diffuse optical spectroscopy, Tissue optics, Spectroscopy, Oximetry, Near infrared

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Proceedings Article | 5 March 2021 Presentation + Paper

“Walking” into freely moving brain monitoring via real-time TD-NIRS

Michele Lacerenza, Mauro Buttafava, Lorenzo Spinelli, Alberto Tosi, Alberto Dalla Mora, Antonio Pifferi, Bruno Cozzi, Alessandro Torricelli, Franco Zappa, Davide Contini

Proceedings Volume 11639, 116390V (2021) https://doi.org/10.1117/12.2578196

KEYWORDS: Brain, Oximetry, Pathology, Tissue optics, Tissues, Standards development, Semiconductor lasers, Oximeters, Near infrared spectroscopy, Medicine

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Proceedings Article | 5 March 2021 Presentation + Paper

Speckle fluctuations in time-domain diffuse optics

Lorenzo Colombo, Saeed Samaei, Pranav Lanka, Daniele Ancora, Marco Pagliazzi, Turgut Durduran, Piotr Sawosz, Adam Liebert, Antonio Pifferi

Proceedings Volume 11641, 116410J (2021) https://doi.org/10.1117/12.2577622

KEYWORDS: Speckle, Diffuse optical imaging, Tissue optics, Tissues, Spectroscopy, Speckle pattern, Scattering, Optical properties, Near infrared, Mode locking

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Proceedings Article | 5 March 2021 Presentation

Preliminary clinical study of the potential of multi-modal optical/ultrasound LUCA platform for improved thyroid cancer screening

Lorenzo Cortese, Giuseppe Lo Presti, Pablo Fernandez Esteberena, Marta Zanoletti, Mauro Buttafava, Marco Renna, Davide Contini, Alberto Dalla Mora, Antonio Pifferi, Paola Taroni, Alberto Tosi, Gloria Aranda, Sabina Ruiz Janer, Mattia Squarcia, Felicia Hanzu, Mireia Mora Porta, Stanislaw Wojtkiewicz, Hamid Dehghani, Udo Weigel, Sixte de Fraguier, An Nguyen-Dinh, Bogdan Rosinski, Turgut Durduran

Proceedings Volume 11639, 116390L (2021) https://doi.org/10.1117/12.2577248

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Proceedings Article | 5 March 2021 Presentation + Paper

SOLUS: an innovative multimodal imaging system to improve breast cancer diagnosis through diffuse optics and ultrasounds

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Christophe Fraschini, Hélène Sportouche, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Proceedings Volume 11639, 116390C (2021) https://doi.org/10.1117/12.2576778

KEYWORDS: Ultrasonography, Multimodal imaging, Imaging systems, Diffuse optical imaging, Breast cancer, Tissue optics, Sensors, Picosecond phenomena, Transducers, Tomography

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SPIE Journal Paper | 22 February 2021 Open Access

Monitoring the motor cortex hemodynamic response function in freely moving walking subjects: a time-domain fNIRS pilot study

Michele Lacerenza, Lorenzo Spinelli, Mauro Buttafava, Alberto Dalla Mora, Franco Zappa, Antonio Pifferi, Alberto Tosi, Bruno Cozzi, Alessandro Torricelli, Davide Contini

NPh, Vol. 8, Issue 01, 015006, (February 2021) https://doi.org/10.1117/12.10.1117/1.NPh.8.1.015006

KEYWORDS: Hemodynamics, Brain, Neurophotonics, Near infrared spectroscopy, Tissues, Functional magnetic resonance imaging, Photons, Electroencephalography, Amplifiers, Absorption

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Proceedings Article | 2 March 2020 Presentation + Paper

Key features in the optical properties of tissue during and after radiofrequency ablation

Francis Kalloor Joseph, Pranav Lanka, Hindrik Kruit, Sanathana Konugolu Venkata Sekar, Andrea Farina, Rinaldo Cubeddu, Srirang Manohar, Antonio Pifferi

Proceedings Volume 11216, 112160H (2020) https://doi.org/10.1117/12.2546042

KEYWORDS: Tissue optics, Optical properties, Radiofrequency ablation, Tissues, Absorption, Scattering, Liver, Electrodes, Biomedical optics, Radio optics

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Proceedings Article | 21 February 2020 Paper

A wearable time domain near infrared spectroscopy system

M. Lacerenza, M. Buttafava, M. Renna, A. Torricelli, A. Tosi, A. Dalla Mora, F. Zappa, A. Pifferi, D. Contini

Proceedings Volume 11237, 1123702 (2020) https://doi.org/10.1117/12.2544271

KEYWORDS: Brain, Near infrared spectroscopy, Hemodynamics, Optical properties, Tissue optics, Tissues, Motion measurement, Absorption, Scattering, In vivo imaging

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Proceedings Article | 22 July 2019 Paper

Solid heterogeneous phantoms for multimodal ultrasound and diffuse optical imaging: an outcome of the SOLUS project for standardization

Laura Di Sieno, Rinaldo Cubeddu, Hélène Sportouche, David Savéry, Sanathana Konugolu Venkata Sekar, Bogdan Rosinski, Andrea Farina, Edoardo Ferocino, Pranav Lanka, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Proceedings Volume 11075, 1107516 (2019) https://doi.org/10.1117/12.2526645

KEYWORDS: Ultrasonography, Optical properties, Diffuse optical imaging, Silicon, Imaging systems, Solids, Multimodal imaging, Tissues, Absorption, Calibration

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SPIE Journal Paper | 12 July 2019 Open Access

Effects of the instrument response function and the gate width in time-domain diffuse correlation spectroscopy: model and validations

Lorenzo Colombo, Marco Pagliazzi, Sanathana Konugolu Venkata Sekar, Davide Contini, Alberto Dalla Mora, Lorenzo Spinelli, Alessandro Torricelli, Turgut Durduran, Antonio Pifferi

NPh, Vol. 6, Issue 03, 035001, (July 2019) https://doi.org/10.1117/12.10.1117/1.NPh.6.3.035001

KEYWORDS: Photons, Sensors, Instrument modeling, Scattering, Optical properties, Picosecond phenomena, Diffusion, Spectroscopes, Absorption, Neurophotonics

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