Sergio Fantini is Professor of Biomedical Engineering and principal investigator of the “Diffuse Optical Imaging of Tissue Laboratory” (DOIT Lab) at Tufts University. The research in the DOIT Lab aims to develop non-invasive techniques based on diffuse optics to assess cerebral perfusion, detect breast cancer, and quantify skeletal muscle oxygenation. One technique developed in the DOIT Lab, coherent hemodynamics spectroscopy (CHS), exploits transients and oscillatory hemodynamic changes to extract physiological information on the investigated tissue. His research resulted in eleven patents and about two hundred scientific publications. He co-authored with Prof. Irving Bigio (Boston University) a textbook on “Quantitative Biomedical Optics.”