Prof. Jianan Y. Qu Profile

Prof. Jianan Y. Qu

Professor at Hong Kong Univ of Science and Technology

SPIE Involvement:

Author | Special Event Speaker

Publications (68)

Proceedings Article | 13 March 2024 Poster + Paper

Adaptive optics two photon microscopy enables in vivo longitudinal visualization of the glaucoma progression with subcellular resolution in the mouse model

Yiming Fu, Binh Minh Pham, Sicong He, Zhongya Qin, Ting Xie, Jianan Qu

Proceedings Volume 12824, 128240H (2024) https://doi.org/10.1117/12.2692203

KEYWORDS: Glaucoma, Adaptive optics, Animal model studies, Silicon, Eye, Retina, Mouse models, Microscopes, Dichroic mirrors, In vivo imaging

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Proceedings Article | 12 March 2024 Presentation + Paper

High resolution two-photon imaging in deep mouse brain through thinned-skull based on alpha-FSS adaptive optics

Zhentao She, Zhongya Qin, Jianan Qu

Proceedings Volume 12847, 128470G (2024) https://doi.org/10.1117/12.2692204

KEYWORDS: Adaptive optics, Skull, Imaging systems, In vivo imaging, Biological imaging, Point spread functions, Fluorescence, Laser ablation, Optical aberrations, Neurons

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Proceedings Article | 21 February 2020 Presentation + Paper

Adaptive optics two-photon microendoscopy for high-resolution and deep-brain imaging in vivo

Congping Chen, Zhongya Qin, Sicong He, Wanjie Wu, Ye Wang, Kam Fai Tam, Nancy Ip, Jianan Qu

Proceedings Volume 11226, 1122606 (2020) https://doi.org/10.1117/12.2546054

KEYWORDS: GRIN lenses, Adaptive optics, In vivo imaging, Imaging systems, Brain, Image resolution, Wavefronts, Brain imaging

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Proceedings Article | 21 February 2020 Paper

In vivo high-resolution multimodal nonlinear optical microscopy of spinal cord in mice

Wanjie Wu, Zhongya Qin, Junqiang Wu, Congping Chen, Weitao Chen, Kai Liu, Jianan Qu

Proceedings Volume 11252, 112520P (2020) https://doi.org/10.1117/12.2546925

KEYWORDS: Adaptive optics, Spinal cord, Axons, In vivo imaging, Microscopy, Luminescence, Imaging systems, Injuries, Microscopes, Surgery

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Proceedings Article | 17 February 2020 Presentation + Paper

Adaptive optics two-photon microscopy for in vivo imaging of mouse retina

Zhongya Qin, Sicong He, Congping Chen, Chao Yang, Jasmine Yung, Wanjie Wu, Christopher Leung, Kai Liu, Jianan Qu

Proceedings Volume 11248, 112480L (2020) https://doi.org/10.1117/12.2546972

KEYWORDS: Adaptive optics, Eye, Retina, Luminescence, In vivo imaging, Retinal scanning, Calcium, Wavefront sensors, Wavefronts

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Proceedings Article | 1 March 2019 Presentation + Paper

Adaptive optics two-photon microscopy for in vivo imaging of cortex and hippocampus in mouse brain

Congping Chen, Zhongya Qin, Sicong He, Caleb Lui, Nancy Ip, Jianan Qu

Proceedings Volume 10865, 108650M (2019) https://doi.org/10.1117/12.2509784

KEYWORDS: Adaptive optics, Skull, GRIN lenses, Brain, In vivo imaging, Neuroimaging, Spine, Wavefronts, Two photon imaging, Image resolution

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Proceedings Article | 23 February 2018 Presentation + Paper

In vivo study of lipid synthesis and lipolysis dynamics by stimulated Raman scattering microscopy

Xuesong Li, Yan Li, Sicong He, Congping Chen, Zhongya Qin, Ho Yi Mak, Jianan Qu

Proceedings Volume 10498, 104981Q (2018) https://doi.org/10.1117/12.2286773

KEYWORDS: Raman spectroscopy, Microscopy, In vivo imaging, Raman scattering, Molecules, Proteins, Optical parametric oscillators, Bandpass filters, Modulation

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Proceedings Article | 23 February 2018 Presentation + Paper

Integrated SRS and fluorescence imaging for study of thermogenesis and lipid metabolism in vivo

Sicong He, Yitai An, Xuesong Li, Zhenguo Wu, Jianan Qu

Proceedings Volume 10498, 104981I (2018) https://doi.org/10.1117/12.2289659

KEYWORDS: Luminescence, Tissues, In vivo imaging, Spectroscopy, Mode conditioning cables, Imaging systems, Imaging spectroscopy, Microscopes, Fluorescence spectroscopy, Nonlinear optics

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Proceedings Article | 20 February 2018 Presentation + Paper

In vivo two-photon imaging of macrophage activities in skeletal muscle regeneration

Zhongya Qin, Yanyang Long, Qiqi Sun, Sicong He, Xuesong Li, Congping Chen, Zhenguo Wu, Jianan Qu

Proceedings Volume 10497, 1049704 (2018) https://doi.org/10.1117/12.2286834

KEYWORDS: Injuries, Second-harmonic generation, In vivo imaging, Two photon imaging, Luminescence, Collagen, Microscopes

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Proceedings Article | 20 February 2018 Paper

Labeling single cell for in-vivo study of cell fate mapping and lineage tracing

Sicong He, Jin Xu, Yi Wu, Ye Tian, Qiqi Sun, Zilong Wen, Jianan Qu

Proceedings Volume 10497, 104970J (2018) https://doi.org/10.1117/12.2286819

KEYWORDS: Infrared lasers, Green fluorescent protein, Temperature metrology, Tissues, Thermometry, In vivo imaging

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Proceedings Article | 12 February 2018 Presentation + Paper

Deep brain two-photon NIR fluorescence imaging for study of Alzheimer’s disease

Congping Chen, Zhuoyi Liang, Biao Zhou, Nancy Ip, Jianan Qu

Proceedings Volume 10481, 104810A (2018) https://doi.org/10.1117/12.2286860

KEYWORDS: Brain, Luminescence, Neuroimaging, Two photon imaging, Alzheimer's disease, Near infrared, In vivo imaging, Skull, Green fluorescent protein, Spectroscopy

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Proceedings Article | 1 May 2017 Presentation

Mechanism and applications of new fluorescent compounds produced by femtosecond laser surgery in biological tissue (Conference Presentation)

Jianan Qu, Qiqi Sun

Proceedings Volume 10060, 100600H (2017) https://doi.org/10.1117/12.2256223

KEYWORDS: Femtosecond phenomena, Laser therapeutics, Surgery, Laser tissue interaction, Multiphoton microscopy, Imaging systems, Tissues, Luminescence, Injuries, Spectroscopy

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Proceedings Article | 21 February 2017 Presentation + Paper

Multimodal nonlinear optical imaging of cartilage development in mouse model

Sicong He, Wenqian Xue, Qiqi Sun, Xuesong Li, Jiandong Huang, Jianan Qu

Proceedings Volume 10069, 100690O (2017) https://doi.org/10.1117/12.2252066

KEYWORDS: Cartilage, Collagen, Second-harmonic generation, Multiphoton microscopy, Mouse models, Harmonic generation, Microscopy, Multimodal imaging, Optical imaging, Proteins, Nonlinear optics, Visualization, Biomedical optics, Luminescence

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SPIE Journal Paper | 18 November 2015 Open Access

Integrated femtosecond stimulated Raman scattering and two-photon fluorescence imaging of subcellular lipid and vesicular structures

Xuesong Li, Wen Jiun Lam, Zhe Cao, Yan Hao, Qiqi Sun, Sicong He, Ho Yi Mak, Jianan Qu

JBO, Vol. 20, Issue 11, 110501, (November 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.11.110501

KEYWORDS: Green fluorescent protein, Imaging systems, Proteins, Nonlinear optics, Luminescence, Microscopes, Raman scattering, Picosecond phenomena, Femtosecond phenomena, Electronic filtering

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SPIE Journal Paper | 27 October 2015 Open Access

Mechanism of two-photon excited hemoglobin fluorescence emission

Qiqi Sun, Wei Zheng, Jiannong Wang, Yi Luo, Jianan Qu

JBO, Vol. 20, Issue 10, 105014, (October 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.10.105014

KEYWORDS: Luminescence, Imaging systems, Absorption, Streak cameras, Proteins, Molecules, Femtosecond phenomena, Picosecond phenomena, Transition metals, Blood

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Proceedings Article | 5 March 2015 Paper

Two-photon excited fluorescence emission from hemoglobin

Qiqi Sun, Yan Zeng, Wei Zhang, Wei Zheng, Yi Luo, Jianan Qu

Proceedings Volume 9329, 93290O (2015) https://doi.org/10.1117/12.2076685

KEYWORDS: Luminescence, Proteins, Single photon, Biology, Signal processing, Molecules, Blood, Catalysis, Electron transport, Gases

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SPIE Journal Paper | 2 April 2013 Open Access

Label-free in vivo imaging of human leukocytes using two-photon excited endogenous fluorescence

Yan Zeng, Bo Yan, Qiqi Sun, Seng Khoon Teh, Wei Zhang, Zilong Wen, Jianan Qu

JBO, Vol. 18, Issue 04, 040504, (April 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.4.040504

KEYWORDS: Luminescence, In vivo imaging, Blood, Visualization, Functional imaging, Synthetic aperture radar, Pathogens, Bacteria, Imaging systems, Proteins

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SPIE Journal Paper | 1 March 2013 Open Access

Multimodal nonlinear optical microscopy improves the accuracy of early diagnosis of squamous intraepithelial neoplasia

Seng Khoon Teh, Wei Zheng, Dong Li, Yan Zeng, Yanqi Yang, Shuxia Li, Jianan Qu

JBO, Vol. 18, Issue 03, 036001, (March 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.3.036001

KEYWORDS: Tissues, Nonlinear optics, Diagnostics, Collagen, Microscopy, Second-harmonic generation, Tissue optics, In vivo imaging, Optical microscopy, Pathology

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Proceedings Article | 22 February 2013 Paper

Two-photon excited endogenous fluorescence for label-free in vivo imaging ingestion of disease-causing bacteria by human leukocytes

Yan Zeng, Bo Yan, Qiqi Sun, Seng Khoon Teh, Wei Zhang, Zilong Wen, Jianan Qu

Proceedings Volume 8588, 85881L (2013) https://doi.org/10.1117/12.2002768

KEYWORDS: Luminescence, Blood, In vivo imaging, Pathogens, Mode conditioning cables, Molecules, Bacteria, Mirrors, Imaging systems, Signal detection

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Proceedings Article | 22 February 2011 Paper

In vivo multiphoton fluorescence microscopy of epithelial precancer

Wei Zheng, Dong Li, Yan Zeng, Jianan Qu

Proceedings Volume 7890, 78900I (2011) https://doi.org/10.1117/12.875925

KEYWORDS: Tissues, Luminescence, Second-harmonic generation, Microscopy, Cancer, Collagen, Signal detection, In vivo imaging, Mode conditioning cables, Optical microscopy

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Proceedings Article | 11 February 2011 Paper

Integrated multiplex CARS and two-photon fluorescence microscopy for imaging biological systems

Dong Li, Wei Zheng, Jianan Qu

Proceedings Volume 7903, 790315 (2011) https://doi.org/10.1117/12.874047

KEYWORDS: Microscopy, Signal detection, Nonlinear optics, Imaging systems, CARS tomography, Second-harmonic generation, Femtosecond phenomena, Luminescence, Optical microscopy, Near infrared

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SPIE Journal Paper | 1 May 2010 Open Access

Monitoring changes of cellular metabolism and microviscosity in vitro based on time-resolved endogenous fluorescence and its anisotropy decay dynamics

Wei Zheng, Dong Li, Jianan Qu

JBO, Vol. 15, Issue 03, 037013, (May 2010) https://doi.org/10.1117/12.10.1117/1.3449577

KEYWORDS: Luminescence, Fluorescence anisotropy, Mode conditioning cables, Molecules, Diffusion, In vitro testing, Anisotropy, Lithium, Statistical analysis, Time resolved spectroscopy

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SPIE Journal Paper | 1 March 2010 Open Access

Clinical study of quantitative diagnosis of early cervical cancer based on the classification of acetowhitening kinetics

Tao Wu, Tak-Hong Cheung, So-Fan Yim, Jianan Qu

JBO, Vol. 15, Issue 02, 026001, (March 2010) https://doi.org/10.1117/12.10.1117/1.3365940

KEYWORDS: Tissues, Diagnostics, Cervix, Cervical cancer, Surface plasmons, Algorithm development, Biopsy, Imaging systems, 3D image processing, Image registration

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Proceedings Article | 26 February 2010 Paper

Multicolor excitation two-photon microscopy: in vivo imaging of cells and tissues

Dong Li, Wei Zheng, Jianan Qu

Proceedings Volume 7569, 756920 (2010) https://doi.org/10.1117/12.841330

KEYWORDS: Luminescence, Tissues, Proteins, In vivo imaging, Second-harmonic generation, Collagen, Two photon excitation microscopy, Microscopy, Imaging systems, Optical filters

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Proceedings Article | 25 February 2010 Paper

Two-photon microscopy of living cells by simultaneously exciting multiple endogenous fluorophores and fluorescent proteins

Wei Zheng, Dong Li, Jianan Qu

Proceedings Volume 7568, 756806 (2010) https://doi.org/10.1117/12.841428

KEYWORDS: Luminescence, Green fluorescent protein, Fluorescent proteins, Femtosecond phenomena, Signal detection, Tissues, Microscopy, Mirrors, Two photon excitation microscopy, In vivo imaging

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SPIE Journal Paper | 1 September 2009 Open Access

Study of cadmium-induced cytotoxicity using two-photon excitation endogenous fluorescence microscopy

Dong Li, Mildred Yang, Tao Lin, Wei Zheng, Jianan Qu

JBO, Vol. 14, Issue 05, 054028, (September 2009) https://doi.org/10.1117/12.10.1117/1.3250293

KEYWORDS: Cadmium, Luminescence, Microscopy, Proteins, Toxicity, Lithium, Metals, Electron transport, Cell death, Electronics engineering

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Proceedings Article | 24 February 2009 Paper

Quantitative optical imaging of early cervical cancer: mechanisms, methods, and clinical study

Tao Wu, Tak-Hong Cheung, So-Fan Yim, Jianan Qu

Proceedings Volume 7187, 71870Y (2009) https://doi.org/10.1117/12.812428

KEYWORDS: Tissues, Cervix, Diagnostics, Cervical cancer, 3D image processing, Algorithm development, Natural surfaces, Principal component analysis, Optical imaging, Cancer

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SPIE Journal Paper | 1 September 2008 Open Access

Autofluorescence of epithelial tissue: single-photon versus two-photon excitation

Wei Zheng, Yicong Wu, Dong Li, Jianan Qu

JBO, Vol. 13, Issue 05, 054010, (September 2008) https://doi.org/10.1117/12.10.1117/1.2975866

KEYWORDS: Luminescence, Tissues, Tissue optics, Collagen, Confocal microscopy, Spectroscopy, Second-harmonic generation, Optical fibers, Fluorescence spectroscopy, Mirrors

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SPIE Journal Paper | 1 May 2008 Open Access

Errata: Unified Mie and fractal scattering by cells and experimental study on application in optical characterization of cellular and subcellular structures

Tao Wu, Jianan Qu, Min Xu

JBO, Vol. 13, Issue 03, 039801, (May 2008) https://doi.org/10.1117/12.10.1117/1.2937889

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SPIE Journal Paper | 1 March 2008 Open Access

Unified Mie and fractal scattering by cells and experimental study on application in optical characterization of cellular and subcellular structures

Min Xu, Tao Wu, Jianan Qu

JBO, Vol. 13, Issue 02, 024015, (March 2008) https://doi.org/10.1117/12.10.1117/1.2907790

KEYWORDS: Light scattering, Scattering, Refractive index, Mie scattering, Fractal analysis, Tissues, Particles, Tumor growth modeling, Spectroscopy, Tissue optics

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Proceedings Article | 22 February 2008 Paper

Signal sources in elastic light scattering by biological cells and tissues: what can elastic light scattering spectroscopy tell us?

M. Xu, Tao Wu, Jianan Qu

Proceedings Volume 6864, 68640Y (2008) https://doi.org/10.1117/12.762368

KEYWORDS: Light scattering, Scattering, Refractive index, Tumor growth modeling, Tissues, Fractal analysis, Spectroscopy, Biomedical optics, Mie scattering, Prostate

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Proceedings Article | 8 January 2008 Paper

Mechanisms of light scattering from biological cells and cell culture

Tao Wu, Jianan Qu

Proceedings Volume 6826, 68260P (2008) https://doi.org/10.1117/12.778579

KEYWORDS: Light scattering, Scattering, Mie scattering, Fractal analysis, Refractive index, Confocal microscopy, Backscatter, Particles, Scatter measurement, Optical testing

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Proceedings Article | 11 July 2007 Paper

Monitoring cellular metabolic pathways by wavelength- and time-resolved intracellular autofluorescence

Yicong Wu, Wei Zheng, Jianan Qu

Proceedings Volume 6628, 662806 (2007) https://doi.org/10.1117/12.727610

KEYWORDS: Luminescence, Mode conditioning cables, Cancer, Time resolved spectroscopy, Fluorescence spectroscopy, Confocal microscopy, Spectroscopy, Detector development, Tissue optics, Proteins

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Proceedings Article | 16 February 2007 Paper

Elastic light scattering by cells: from Mie scattering to fractal scattering

M. Xu, Tao Wu, Jianan Qu

Proceedings Volume 6446, 64460Y (2007) https://doi.org/10.1117/12.700859

KEYWORDS: Light scattering, Scattering, Mie scattering, Refractive index, Fractal analysis, Particles, Tissue optics, Superposition, Biomedical optics, Tissues

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Proceedings Article | 15 February 2007 Paper

Light scattering spectroscopy of cells: a study based on Mie and fractal models

Tao Wu, Min Xu, Jianan Qu

Proceedings Volume 6446, 64460H (2007) https://doi.org/10.1117/12.697141

KEYWORDS: Light scattering, Scattering, Mie scattering, Fractal analysis, Refractive index, Tissues, Spectroscopy, Scatter measurement, Glasses, Optical spheres

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Proceedings Article | 6 February 2007 Paper

Detection of cell metabolism via wavelength- and time-resolved intracellular autofluorescence

Yicong Wu, Wei Zheng, Jianan Qu

Proceedings Volume 6430, 64300A (2007) https://doi.org/10.1117/12.702459

KEYWORDS: Luminescence, Mode conditioning cables, Confocal microscopy, Cancer, Time resolved spectroscopy, Fluorescence spectroscopy, Hypoxia, Tissues, Electron transport, Single photon

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Proceedings Article | 6 February 2007 Paper

Time-resolved confocal fluorescence spectroscopy reveals the structure and metabolic state of epithelial tissue

Yicong Wu, Wei Zheng, Jianan Qu

Proceedings Volume 6430, 643013 (2007) https://doi.org/10.1117/12.702450

KEYWORDS: Luminescence, Tissues, Confocal microscopy, Fluorescence spectroscopy, Tissue optics, Collagen, Time resolved spectroscopy, Cancer, Spectroscopy, Mode conditioning cables

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SPIE Journal Paper | 1 September 2006 Open Access

Autofluorescence spectroscopy of epithelial tissues

Yicong Wu, Jianan Qu

JBO, Vol. 11, Issue 05, 054023, (September 2006) https://doi.org/10.1117/12.10.1117/1.2362741

KEYWORDS: Luminescence, Tissues, Collagen, Fluorescence spectroscopy, Spectroscopy, Confocal microscopy, Mode conditioning cables, Scattering, Colon, Cancer

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Proceedings Article | 25 February 2006 Paper

Combined time- and depth-resolved autofluorescence spectroscopy for tissue diagnosis

Yicong Wu, Jianan Qu

Proceedings Volume 6080, 608018 (2006) https://doi.org/10.1117/12.651391

KEYWORDS: Luminescence, Tissues, Tissue optics, Collagen, Fluorescence spectroscopy, Time resolved spectroscopy, Confocal microscopy, Spectroscopy, Pathology, Biochemistry

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Proceedings Article | 22 June 2005 Paper

Depth-resolved fluorescence of biological tissue

Yicong Wu, Peng Xi, Tak-Hong Cheung, So Fan Yim, Mei-Yung Yu, Jianan Qu

Proceedings Volume 5771, (2005) https://doi.org/10.1117/12.634626

KEYWORDS: Luminescence, Tissues, Tissue optics, Pathology, Fluorescence spectroscopy, Confocal microscopy, Collagen, Laser tissue interaction, Natural surfaces, Diagnostics

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Proceedings Article | 1 April 2005 Paper

Depth-resolved fluorescence of human ectocervical tissue

Yicong Wu, Peng Xi, Tak-Hong Cheung, So Fan Yim, Mei-Yung Yu, Jianan Qu

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.593826

KEYWORDS: Luminescence, Tissues, Tissue optics, Collagen, Pathology, Confocal microscopy, Fluorescence spectroscopy, Laser tissue interaction, Natural surfaces, Connective tissue

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Proceedings Article | 1 April 2005 Paper

Study of acetowhitening method to distinguish normal and cancerous tissue at cellular level

Tao Wu, Tak-Hong Cheung, So Fan Yim, Yick Fu Wong, Jianan Qu

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.593822

KEYWORDS: Tissues, Cancer, Cervical cancer, Microscopes, Light scattering, Backscatter, Proteins, Data acquisition, Cervix, Optical properties

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Proceedings Article | 18 January 2005 Paper

Confocal fluorescence spectroscopy system for detecting early-stage cancer

Wumei Lin, Yicong Wu, Tingwen Xing, Jianan Qu

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.570962

KEYWORDS: Tissues, Luminescence, Confocal microscopy, Tissue optics, Fluorescence spectroscopy, Cancer, Calibration, Signal to noise ratio, Natural surfaces, Diagnostics

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Proceedings Article | 21 June 2004 Paper

Fluorescence spectroscopy of biological tissue: single- and two-photon excitation

Yicong Wu, Peng Xi, Weikun Ge, Powing Yuen, Jianan Qu

Proceedings Volume 5323, (2004) https://doi.org/10.1117/12.544404

KEYWORDS: Luminescence, Tissues, Fluorescence spectroscopy, Confocal microscopy, Tissue optics, Collagen, Connective tissue, Spectroscopy, Esophagus, Pathology

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SPIE Journal Paper | 1 January 2004 Open Access

Classification of in vivo autofluorescence spectra using support vector machines

Wumei Lin, Xin Yuan, Po Wing Yuen, William Wei, Jonathan Sham, Peng-Cheng Shi, Jianan Qu

JBO, Vol. 9, Issue 01, (January 2004) https://doi.org/10.1117/12.10.1117/1.1628244

KEYWORDS: Algorithm development, Tissues, Principal component analysis, Diagnostics, In vivo imaging, Detection and tracking algorithms, Endoscopy, Spectroscopy, Biopsy, Tumors

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Proceedings Article | 8 October 2003 Paper

Combined classifier for discriminating cancerous tissue from normal tissue using light-induced autofluorescence

Wumei Lin, Xin Yuan, Po Wing Yuen, Jonathan Sham, William Wei, Yue Wen, Peng-Cheng Shi, Jianan Qu

Proceedings Volume 5141, (2003) https://doi.org/10.1117/12.500406

KEYWORDS: Principal component analysis, Tissues, Algorithm development, Tissue optics, In vivo imaging, Spectroscopy, Diagnostics, Endoscopy, Biopsy, Detection and tracking algorithms

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Proceedings Article | 8 October 2003 Paper

Fluorescence detection of neoplastic growths in vivo

Tao Wu, T. H. Cheung, K. W. Lo, Yue Wen, Jianan Qu

Proceedings Volume 5141, (2003) https://doi.org/10.1117/12.500011

KEYWORDS: Tissues, Luminescence, Tissue optics, Imaging systems, Calibration, Reflection, Absorption, In vivo imaging, Optical properties, Scattering

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Proceedings Article | 22 July 2003 Paper

Miniaturized 3D endoscopic imaging system

Manhong Chan, Changhe Zhou, Jianan Qu

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.477878

KEYWORDS: 3D image processing, Endoscopy, Imaging systems, Endoscopes, 3D metrology, Surgery, 3D acquisition, 3D modeling, Calibration, Structured light

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Proceedings Article | 22 July 2003 Paper

Detecting neoplastic growths in vivo with autofluorescence imaging

Tao Wu, T. Cheung, K. Lo, Jianan Qu

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.479804

KEYWORDS: Tissues, Luminescence, Tissue optics, Imaging systems, Reflection, Calibration, In vivo imaging, Absorption, Scattering, Optical properties

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Proceedings Article | 22 July 2003 Paper

Preliminary study of a dual-CCD-based ratiometric optical mapping system

David Tang, Yuhua Li, Jianan Qu, Sunny Po, Eugene Patterson, Wei Chen, Warren Jackman, Hong Liu

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.488683

KEYWORDS: Luminescence, Tissues, Optical filters, Action potentials, CCD cameras, Charge-coupled devices, Sensors, Signal detection, Data acquisition, Temporal resolution

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Proceedings Article | 16 July 2002 Paper

Calibrated autofluorescence imaging for classification of tissue and detection of early cervical cancer

Jianan Qu, T. H. Cheung, Jianwen Hua, W.K. Lo

Proceedings Volume 4707, (2002) https://doi.org/10.1117/12.475578

KEYWORDS: Tissues, Luminescence, Calibration, Laser induced fluorescence, In vivo imaging, Cervix, Cervical cancer, Auto-fluorescence imaging, Reflection, Natural surfaces

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Proceedings Article | 31 October 2001 Paper

Light-induced autofluorescence for detection of nasopharyngeal carcinoma in vivo

Hanpeng Chang, Yue Wen, Siu Lee, Po Yuen, William Wei, Jonathan Sham, Jianan Qu

Proceedings Volume 4432, (2001) https://doi.org/10.1117/12.447134

KEYWORDS: Tissues, Diagnostics, Principal component analysis, Laser induced fluorescence, Algorithm development, Calibration, Tissue optics, In vivo imaging, Statistical analysis, Luminescence

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Proceedings Article | 8 May 2000 Paper

Rapid quantification of the clinically important analytes in sub-ul simulating human sera

Jianan Qu, Lan Shao

Proceedings Volume 3918, (2000) https://doi.org/10.1117/12.384938

KEYWORDS: Raman spectroscopy, Capillaries, Urea, Glucose, Analytical research, Biological research, Calibration, Molecules, Chemical analysis, Statistical analysis

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Proceedings Article | 19 April 2000 Paper

Combination of diffuse reflectance and fluorescence imaging of turbid media

Jianan Qu, Jianwen Hua, Zhijian Huang

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382749

KEYWORDS: Luminescence, Tissues, Reflection, Scattering, Blood, Tissue optics, Absorption, Specular reflections, Natural surfaces, Optical properties

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Proceedings Article | 19 April 2000 Paper

In-vivo autofluorescence of nasopharyngeal carcinoma and normal tissue

Jianan Qu, Po Yuen, Zhijian Huang, William Wei

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382732

KEYWORDS: Luminescence, Tissues, In vivo imaging, Endoscopy, Imaging systems, Endoscopes, Biopsy, Blood, Imaging spectroscopy, Tissue optics

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Proceedings Article | 9 July 1999 Paper

Improved accuracy of quantification of analytes in human body fluids by near-IR laser Raman spectroscopy with new algorithms

Jianan Qu, On Yau, SzeFong Yau

Proceedings Volume 3595, (1999) https://doi.org/10.1117/12.351525

KEYWORDS: Raman spectroscopy, Chemical analysis, Calibration, Bioalcohols, Statistical analysis, Principal component analysis, Biological research, Laser spectroscopy, Molecules, Analytical research

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Proceedings Article | 30 April 1999 Paper

Imaging water absorption with OCT

Joseph Schmitt, Jianwen Hua, Jianan Qu

Proceedings Volume 3598, (1999) https://doi.org/10.1117/12.347505

KEYWORDS: Absorption, Optical coherence tomography, Scattering, Signal attenuation, Light emitting diodes, Tissues, Skin, Liquids, Backscatter, Tissue optics

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Proceedings Article | 1 May 1998 Paper

Application of laser Raman spectroscopy in concentration measurements of multiple analytes in human body fluids

Jianan Qu, David Suria, Brian Wilson

Proceedings Volume 3253, (1998) https://doi.org/10.1117/12.308044

KEYWORDS: Raman spectroscopy, Biological research, Proteins, Glucose, Chemical analysis, Bioalcohols, Diagnostics, Chemistry, Molecules, Near infrared

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Proceedings Article | 24 April 1998 Paper

Interpretation and processing of NIR spectra of turbid biological tissue

Joseph Schmitt, Hua Yang, Jianan Qu

Proceedings Volume 3257, (1998) https://doi.org/10.1117/12.306079

KEYWORDS: Scattering, Tissues, Absorption, Near infrared, Reflectivity, Spectroscopy, Skin, Near infrared spectroscopy, Diffusion, Sensors

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Proceedings Article | 18 August 1997 Paper

Feasibility studies of focused ultrasound for spatial localization of optical signals in multiply scattering media

Kai Zhang, Lothar Lilge, Andrew Klug, Jianan Qu, Victor Yang, Brian Wilson

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280282

KEYWORDS: Ultrasonography, Signal detection, Tissue optics, Modulation, Sensors, Diffraction, Photons, Scattering, Speckle pattern, Optical properties

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SPIE Journal Paper | 1 July 1997 Open Access

Monte Carlo modeling studies of the effect of physiological factors andother analytes on the determination of glucose concentration in vivoby near infrared optical absorption and scattering measurements

Jianan Qu, Brian Wilson

JBO, Vol. 2, Issue 03, (July 1997) https://doi.org/10.1117/12.10.1117/12.275453

KEYWORDS: Glucose, Water, Tissues, Absorption, Tissue optics, Scattering, Refractive index, Transmittance, Monte Carlo methods, Light scattering

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Proceedings Article | 5 April 1996 Paper

Effect of physiological factors and other analytes on the determination of glucose concentration in vivo by optical absorption and scattering meaurements

Jianan Qu, Brian Wilson

Proceedings Volume 2679, (1996) https://doi.org/10.1117/12.237593

KEYWORDS: Glucose, Water, Absorption, Tissue optics, Tissues, Scattering, Proteins, Transmittance, Light scattering, Refractive index

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SPIE Journal Paper | 1 November 1995

Laser-induced fluorescence spectroscopy at endoscopy: tissue optics, Monte Carlo modeling, and in vivo measurements

Jianan Qu, Calum MacAulay, Stephen Lam, Branko Palcic

OE, Vol. 34, Issue 11, (November 1995) https://doi.org/10.1117/12.10.1117/12.212917

KEYWORDS: Luminescence, Tissues, Blood, In vivo imaging, Tissue optics, Laser induced fluorescence, Monte Carlo methods, Absorption, Optical properties, In vitro testing

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Proceedings Article | 12 May 1995 Paper

Optical properties of normal and malignant tissues in the nasopharynx and larynx

Calum MacAulay, Stephen Lam, Jianan Qu, C. Man, M. Harries, Branko Palcic

Proceedings Volume 2395, (1995) https://doi.org/10.1117/12.209097

KEYWORDS: Tissues, Lung, Optical properties, Copper indium disulfide, Cancer, Fiber optics, Absorption, In vivo imaging, Biopsy, Luminescence

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Proceedings Article | 12 April 1995 Paper

Mechanisms of ratio fluorescence imaging of diseased tissue

Jianan Qu, Calum MacAulay, Stephen Lam, Branko Palcic

Proceedings Volume 2387, (1995) https://doi.org/10.1117/12.206806

KEYWORDS: Luminescence, Tissues, Tissue optics, Tumor growth modeling, Monte Carlo methods, Blood, In vivo imaging, Copper indium disulfide, Optical properties, Laser tissue interaction

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Proceedings Article | 17 August 1994 Paper

Fluorescence in normal and carcinoma bronchial tissue

Jianan Qu, Calum MacAulay, Stephen Lam, Haishan Zeng, Branko Palcic

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182938

KEYWORDS: Tissues, Luminescence, Monte Carlo methods, Optical properties, Optical spectroscopy, Absorption, Light scattering, Scattering, Anisotropy, Collimation

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Proceedings Article | 19 July 1994 Paper

Laser-induced fluorescence spectroscopy at endoscopy

Jianan Qu, Calum MacAulay, Stephen Lam, Branko Palcic

Proceedings Volume 2133, (1994) https://doi.org/10.1117/12.179979

KEYWORDS: Tissues, Luminescence, Cancer, Monte Carlo methods, Laser induced fluorescence, Spectroscopy, Endoscopy, Fluorescence spectroscopy, Tumors, In vivo imaging

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Proceedings Article | 18 June 1993 Paper

Fluorescence imaging of premalignant and malignant tissues with and without photosensitizers

Stephen Lam, Calum MacAulay, Jean Le Riche, Jianan Qu, Gorazd Krosl, Haishan Zeng, Mladen Korbelik, Branko Palcic

Proceedings Volume 1881, (1993) https://doi.org/10.1117/12.146306

KEYWORDS: Luminescence, Lung cancer, Tissues, Tumors, Cancer, Bronchoscopy, Helium cadmium lasers, Tumor growth modeling, Imaging devices, CCD cameras

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